摘要
目的对缺铁性贫血(IDA)和地中海贫血(TT)常用实验室血液检查结果进行比较,以期为临床鉴别诊断提供依据。方法回顾性收集清远市妇幼保健院门诊和住院部2011年1月-2018年5月收治的小细胞低色素性贫血患者186例,分为IDA组108例和TT组78例,比较两组患者血常规和骨髓、外周血涂片结果。结果两组红细胞计数、血红蛋白浓度、平均红细胞体积、平均红细胞血红蛋白浓度和红细胞分布宽度水平差异有统计学意义(P<0.05);而平均红细胞血红蛋白含量水平差异无统计学意义(P>0.05)。IDA组外周血和骨髓涂片靶形红细胞少见或未见;TT组靶形红细胞多见。骨髓铁染色下,IDA组细胞外铁和细胞内铁减少或缺乏,而TT组细胞外铁和细胞内铁增加。结论IDA和TT临床鉴别诊断存在一定困难,需要结合多种实验室检查以明确诊断。
Objective To compare the routine blood test results of IDA and TT in order to provide evidence for clinical differential diagnosis.Methods A total of 186 patients with small cell hypochromic anemia admitted to our hospital from January 2011 to May 2018 were retrospectively collected.They were divided into IDA group(108 cases)and TT group(78 cases).The results of routine blood examination,bone marrow and peripheral blood smears were compared between the two groups.Results There were significant differences in RBC,Hb,MCV,MCHC and RDW levels between the two groups(P<0.05),but there was no significant difference in MCH levels(P>0.05).Target cells were rare or not seen on peripheral blood and bone marrow smears in IDA group,but more in TT group.Extracellular and intracellular iron staining of bone marrow reduced or lacked in IDA group,but increased in TT group.Conclusion It is difficult to differentiate IDA from TT in clinical diagnosis.It is necessary to combine various laboratory examinations to make a definite diagnosis.
作者
祝少凤
梁桂兰
欧阳慧
ZHU Shaofeng;LIANG Guilan;OUYANG Hui(Clinical Laboratory,Qingyuan Maternity & Child Healthcare Hospital,Qingyuan 511500,Guangdong Province,China)
出处
《中国实用乡村医生杂志》
2019年第6期49-51,54,共4页
Chinese Practical Journal of Rural Doctor
关键词
缺铁性贫血
地中海贫血
鉴别
诊断
Iron Deficiency Anemia
Thalassemia
Differentiation
Diagnosis
