摘要
目的探讨射频消融术治疗子宫肌瘤的疗效观察及对患者卵巢功能和预后的影响。方法选择2015年6月至2016年6月间本院收治的子宫肌瘤患者92例作为观察对象,根据治疗方法的不同进行分组,行腹腔镜下子宫肌瘤剔除术设为对照组(n=46),行射频消融术的设为观察组(n=46)。比较两组患者的围术期相关指标,术前及术后卵巢功能的变化情况。结果观察组患者的术中出血量、手术时间、住院时间及术后复常时间均少于对照组,差异具有统计学意义(P<0.05);术前,两组患者的FSH、LH、E2、AFC水平比较,差异无统计学意义;术后1月,两组患者的FSH、LH、E2水平均升高,而AFC水平降低;且观察组FSH、LH、E2水平低于对照组,AFC水平高于对照组,差异具有统计学意义(P<0.05)。术后随访2年,观察组妊娠成功率88.89%,高于对照组的64.00%,差异具有统计学意义(P<0.05)。结论与腹腔镜下子宫肌瘤剔除术比较,射频消融术具有创伤小、恢复快等优点,且对患者卵巢功能影响较小,妊娠成功率高,值得临床推广使用。
Objective To investigate the efficacy of radiofrequency ablation in the treatment of uterine fibroids and its effect on ovarian function and prognosis.Methods 92 patients with uterine fibroids admitted to our hospital from June 2015 to June 2016 were selected as observation subjects.According to the different treatment methods,laparoscopic myomectomy was used in the control group(n=46),and radiofrequency ablation was performed in the observation group(n=46).Perioperative-related indicators,changes in ovarian function before and after surgery were compared between the two groups.Results The intraoperative blood loss,operation time,hospitalization time and postoperative recurrence time of the observation group were lower than those of the control group,the difference was statistically significant(P<0.05).Before operation,the FSH,LH and E2 of the two groups of patients,there was no significant difference in AFC level.At 1 month after operation,the FSH,LH,and E2 levels of the two groups increased,while the AFC level decreased.The FSH,LH,and E2 levels in the observation group were low.In the control group,the AFC level was higher than the control group,and the difference was statistically significant(P<0.05).After 2 years of follow-up,the pregnancy success rate of the observation group was 88.89%,which was higher than that of the control group(64.00%).The difference was statistically significant(P<0.05).Conclusion Compared with laparoscopic myomectomy,radiofrequency ablation has the advantages of small trauma and quick recovery,and has little effect on ovarian function and high pregnancy success rate,it is worthy of clinical promotion.
作者
郭淑珍
Guo Shuzhen(Obstetrics and Gynecology of Huimin People' s Hospital,Binzhou,Shandong,251700,China)
出处
《当代医学》
2019年第19期53-55,共3页
Contemporary Medicine
