摘要
目的探讨双源CT冠状动脉造影评价原发性高血压(EH)、2型糖尿病(DM)及高血压合并糖尿病(EH+DM)左心功能的差异性。方法选择该院2017年9月-2018年7月心内科住院患者,确诊为EH患者68例,为EH组;DM患者64例,为DM组;69例高血压合并糖尿病患者,为EH+DM组。同期收集60名健康患者作为对照组。所有患者均行双源CT冠状动脉血管造影,并对三组患病组冠脉狭窄情况及四组的左心功能进行比较,包括左心室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、左室每搏输出量(LVSV)、左心室射血分数(LVEF)、心脏指数(CI)、左室心肌质量(LVMM)及左心室后壁厚度(LVPWT)。结果EH+DM组冠脉狭窄处最多,EH组与DM组冠脉狭窄处无明显差异。DM组EF值低于对照组,EH+DM组EF值不仅低于对照组,并且低于EH组与DM组(P<0.05);EH组EF值稍低于正常组,但差异无统计学意义(P>0.05)。EH组及DM组LVEDV、LVESV、LVPWT以及EH+DM组LVEDV、LVESV、CI、LVPWT均高于对照组,其中EH+DM组LVEDV高于EH组与DM组,EH+DM组CI高于DM组(P<0.05);EH组与DM组对照,所有的值差异无统计意义。结论高血压、糖尿病会对左心室收缩和舒张功能产生一定的影响,造成左心功能减退,尤其是糖尿病合并高血压患者左心功能减退更加明显。而双源CT冠状动脉血管造影有利于糖尿病合并高血压患者左心功能评价。
Objective To investigate the difference of left ventricular function in patients with essential hypertension(EH),type 2 diabetes(DM)and hypertension with diabetes(EH+DM)by dual-source CT coronary angiography.Methods The hospitalized patients in our hospital from September 2017 to July 2018 were enrolled.68 patients with EH were diagnosed as EH group;64 patients with DM were DM group;69 patients with hypertension and diabetes were EH+DM group.60 healthy patients were collected as a control group during the same period.All patients underwent dual-source CT coronary angiography and compared coronary stenosis in the three groups and left ventricular function in the four groups,including left ventricular end-diastolic volume(LVEDV)and left ventricular end-systolic volume(LVESV),left ventricular stroke volume(LVSV),left ventricular ejection fraction(LVEF),cardiac index(CI),left ventricular mass(LVMM),and left ventricular posterior wall thickness(LVPWT).Results The EH+DM group had the most coronary stenosis,and there was no significant difference between the EH group and the DM group.The EF value of DM group was lower than that of the control group.The EF value of EH+DM group was not only lower than that of the control group,but also lower than that of EH group and DM group(P<0.05).The EF value of EH group was slightly lower than that of normal group,but the difference was not statistically significant(P>0.05).The LVEDV,LVESV,CI and LVPWT in the LVEDV,LVESV,LVPWT and EH+DM groups in the EH group and the DM group were higher than those in the control group,among which the LVEDV in the EH+DM group was higher than that in the EH group and the DM group,and the CI in the EH+DM group was higher than the DM group(P<0.05);the EH group was compared with the DM group,and all the values were not statistically significant.Conclusion Hypertension and diabetes have certain effects on left ventricular systolic and diastolic function,resulting in left ventricular dysfunction,especially in patients with diabetes and hypertension.Dual-source CT coronary angiography is helpful for the evaluation of left ventricular function in patients with diabetes mellitus complicated with hypertension.
作者
陈梅桂
赖清泉
魏丽珍
余雄峰
CHEN Mei-gui;LAI Qing-quan;WEI Li-zhen;YU Xiong-feng(The Second Affiliated Hospital of Fujian Medical University,Quanzhou,Fujian Province,362000 China)
出处
《糖尿病新世界》
2019年第9期13-16,共4页
Diabetes New World Magazine
基金
泉州市科技计划项目(2018Z129)
关键词
双源CT
高血压
糖尿病
左心功能
Dual source CT
Hypertension
Diabetes
Left heart function
