摘要
目的:评价Ahmed青光眼引流装置植入术与传统小梁切除术(Trab)治疗难治性青光眼的疗效。方法:运用Cochrance系统评价方法,使用相关数据库检索关于Ahmed引流阀植入术与传统Trab术治疗难治性青光眼效果比较的随机对照试验(RCT)文献。观察两种手术的眼压下降幅度百分比(IOPR%)及使用与未使用抗青光眼药物达到目标IOP成功率。结果:共293例患者(293只眼)被纳入此次Meta分析,其中Ahmed组146只、Trab组147只;两组术后随访结束时IOPR%比较,差异无统计学意义[MD=-0.59,95%CI=(-7.48,6.29),P>0.05];术后1年无论是否抗青光眼药物,Trab组达到目标IOP成功率均低于Ahmed组(P<0.05)。结论:在治疗青光眼的手术中,传统Trab术与Ahmed引流阀植入术组有相似的降低IOP效果,但Ahmed引流阀植入术达到目标IOP成功率较高。
Objective:To evaluate the efficacy of Ahmed glaucoma drainage device implantation and trabeculectomy(Trab)in treatment of refractory glaucoma.Method:The Cochrance system evaluation method was used to retrieve the literature of randomized controlled trials(RCT)on the efficacy of Ahmed drainage valve implantation compared with traditional Trab in treatment of refractory glaucoma.The IOP reduction rate(IOPR%)and the success rate of IOP with or without antiglaucoma drugs were observed.Result:A total of 293 patients(293 eyes)were included in the Meta-analysis,included 146 in Ahmed group and 147 in Trab group.At the end of follow-up,the IOPR%in two groups was compared,the differences was not statistically significant[MD=-0.59,95%CI=(-7.48,6.29),P>0.05].After surgery 1 year,whether or not anti-glaucoma drugs were used,The successful rate of achieving IOP of Trab group were lower than those of Ahmed group(P<0.05).Conclusion:In glaucoma surgery,traditional Trab and Ahmed drainage valve implantation have similar effect in reducing IOP,but the success rate of Ahmed drainage valve implantation is higher.
作者
彭静
PENG Jing(Meizhou People’s Hospital,Meizhou 514000,China)
出处
《中国医学创新》
CAS
2019年第16期161-165,共5页
Medical Innovation of China
基金
2016年梅州市医药卫生科研立项项目(2016-B-18)
