摘要
目的分析重症病毒性肺炎(VP)合并急性呼吸窘迫综合征(ARDS)预后的危险因素。方法选择2017年12月~2018年12月本院收治的100例重症VP合并ARDS患者的临床资料进行回顾性分析,根据住院期间是否死亡分为生存组(n=44例)与死亡组(n=56例),比较两组相关因素情况。结果两组患者在性别、呼吸频率、脉搏、凝血酶原时间(PT)、尿素氮(BUN)、肌酐(Sc)、C反应蛋白(CRP)、血沉(ESR)、血清降钙素原(PCT)上比较无显著差异(P> 0.05),但两组在年龄、住院时间、氧合指数、机械通气时间、ARDS分度上差异显著(P <0.05),将有统计学意义的因素进一步实施多因素logistic分析分析,发现住院时间<7d、机械通气时间<7d、ARDS分度重度属于危险因素(P <0.05)。结论重症VP合并ARDS患者预后可能受到年龄、氧合指数、住院时间、机械通气时间及ARDS分度等因素影响,而住院时间<7d、机械通气时间<7d、ARDS分度重度属于危险因素,应尽早分析与处理,减少死亡。
Objective To analyze the risk factors for prognosis of severe viral pneumonia (VP) complicated with acute respiratory distress syndrome (ARDS). Methods The clinical data of 100 patients with severe VP complicated with ARDS admitted to our hospital from December 2017 to December 2018 were retrospectively analyzed. According to whether death occurred during hospitalization, the patients were divided into survival group (n=44 cases) and death group (n=56 cases), and the related factors of the two groups were compared. Results There were no significant differences in gender, respiratory frequency, pulse, prothrombin time (PT), urea nitrogen (BUN), creatinine (Sc), c-reactive protein (CRP), ESR and serum procalcitonin (PCT) between the two groups (P > 0.05), but there were significant differences in age, hospitalization time, oxygenation index, mechanical ventilation time and ARDS index between the two groups (P < 0.05). Multivariate logistic regression analysis was further carried out on statistically significant factors. It was found that hospitalization time < 7 d, mechanical ventilation time < 7 d, ARDS grade severity were risk factors (P < 0.05). Conclusion The prognosis of patients with severe VP complicated with ARDS may be affected by age, oxygenation index, hospitalization time, mechanical ventilation time and ARDS index, while hospitalization time < 7d, mechanical ventilation time < 7 d and ARDS index severity are risk factors, which should be analyzed and treated as early as possible to reduce death mortality.
作者
刘江帆
李朝红
LIU Jiang-fan;LI Chao-hong(Henan Provincial Third People's Hospital, Zhengzhou, Henan, 450000, China)
出处
《临床研究》
2019年第7期6-7,共2页
Clinical Research
关键词
重症病毒性肺炎
急性呼吸窘迫综合征
生存
死亡
预后
severe viral pneumonia
acute respiratory distress syndrome
survival
death
prognosis
