摘要
胃食管反流疾病(GERD)是指胃内容物反流到食管而引起不适症状和(或)并发症的上消化道疾病。质子泵抑制剂是治疗GERD的首选药物,但对难治性GERD的患者疗效欠佳,而抗反流手术能有效地治疗这部分患者。内镜下抗反流手术包括经口无切口折叠术(TIF)、射频消融疗法(Stretta术)、抗反流黏膜切除术(ARMS)和内镜下注射或植入技术。外科抗反流手术包括胃底折叠术、磁控括约肌增强技术(MSA)、LES电刺激术及减肥手术。文章重点阐述抗反流手术应用于胃食管反流疾病的治疗。
Gastroesophageal reflux disease(GERD)is defined as refluxing of gastric contents to the esophagus,causing gastrointestinal tract symptoms and/or complications. Proton pump inhibitors are the first choice for the treatment of GERD,but have no such good effect as anti-reflux surgery on refractory GERD. Endoscopic anti-reflux procedures include transoral incisionless fundoplication(TIF),Stretta radiofrequency ablation,anti-reflux mucosectomy(ARMS),and endoscopic injection or implantation. Anti-reflux surgery involves laproscopic Nissen fundoplication(LNF),magnetic sphincter augmentation(MSA),electrical stimulation on the lower esophageal sphincter(LES),and bariatric surgery. This article introduces the progress in anti-reflux surgery for GERD.
作者
陈嘉伟
范志宁
CHEN Jia-wei;FAN Zhi-ning(Department of Digestive Endoscopy,the First Affiliated Hospital with Nanjing Medical University,Nanjing 210029,Jiangsu,China)
出处
《医学研究生学报》
CAS
北大核心
2019年第6期580-585,共6页
Journal of Medical Postgraduates
关键词
胃食管反流性疾病
质子泵抑制剂
抗反流手术
gastroesophageal reflux disease
proton pump inhibitors
anti-reflux surgery
