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基于“虚、毒、瘀”浅述芪参颗粒治疗慢性心力衰竭气虚血瘀证中医理论依据 被引量:31

Explaining the TCM Theoretical Basis of Qishen Granules in the Treatment of Chronic Heart Failure with Qi Deficiency and Blood Stasis Syndrome from the Perspective of “Deficiency,Toxicity,Stasis”
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摘要 慢性心力衰竭是临床常见病、复杂病,越来越多的研究发现,“虚、毒、瘀”构成了慢性心力衰竭的病机要素。基于此,王伟教授创制了芪参颗粒一方,取其益气温阳、活血化瘀、清热解毒之功,而行改善心功能、减轻心室重构之效。基于“虚、毒、瘀”三要素,阐述其在心力衰竭发病过程中的作用,并对芪参颗粒的组方依据及其基础研究成果进行解释分析,或可为慢性心力衰竭的中医治疗提供思路和参考。 Chronic heart failure is a common and complex disease.More and more studies have found that “deficiency,toxicity and stasis” constitute the pathogenesis of chronic heart failure.Based on this,Prof.Wang Wei created the “Qishen Granules”,taking the functions of nourishing qi and warming yang,promoting blood circulation,clearing heat and detoxification,and improving heart function and attenuating ventricular remodeling.Based on the 3 elements of “deficiency,toxicity and stasis”,this paper described their roles in the pathogenesis of heart failure,and elaborated on the formula basis and basic research results of Qishen Granules,which may provide ideas and references for the treatment of chronic heart failure.
作者 刘俊杰 赵慧辉 张建 孙晓丽 王金平 王娟 王伟 Liu Junjie;Zhao Huihui;Zhang Jian;Sun Xiaoli;Wang Jinping;Wang Juan;Wang Wei(Beijing University of Chinese Medicine,Beijing 100029,China;Beijing Key Laboratory of Syndrome andPrescription Basic Research,Beijing 100029,China;Ministry of Education Key Laboratory of Syndromeand Prescription Basic Research,Beijing 100029,China)
出处 《世界中医药》 CAS 2019年第6期1447-1449,共3页 World Chinese Medicine
基金 国家重点研发计划资助项目(2017YFC1700102)——心衰气虚证的辨证标准研究 北京中医药大学创新团队(2011-CXTD-06)
关键词 慢性心力衰竭 芪参颗粒 气虚血瘀证 Chronic heart failure Qishen Granules Qi deficiency and blood stasis syndrome Deficiency Toxicity Stasis
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