摘要
终末期肝病合并侵袭性真菌感染患者的病死率高。其临床表现常不典型,诊断上存在一定难度,且抗真菌药物存在诸如肝肾毒性、药物相互作用和耐药等临床问题,终末期肝病合并侵袭性真菌感染的治疗面临较大挑战。本文将主要围绕终末期肝病合并侵袭性真菌感染的治疗进行综述。
The patients with end-stage liver disease (ESLD) complicated with invasive fungal infection (IFI) have a high mortality. Atypical clinical manifestations, certain difficulties in the diagnosis, liver and kidney toxicity of anti-fungal agents, drug-drug interactions and drug resistance totally lead to a great challenge in clinical treatment of ESLD complicated with IFI. The present article summarizes the treatment of ESLD complicated with IFI.
作者
杨中原
陈韬
YANG Zhong-yuan;CHEN Tao(Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China)
出处
《传染病信息》
2019年第3期199-202,共4页
Infectious Disease Information
基金
国家自然科学基金青年基金(81600471)
关键词
终末期肝病
侵袭性真菌感染
治疗
end-stage liver disease
invasive fungal infection
treatment
