摘要
目的探讨丹红六君子汤联合常规治疗对慢性阻塞性肺疾病患者的临床疗效。方法 120例患者随机分为对照组和观察组,每组60例,对照组给予常规治疗,观察组在对照组基础上加用丹红六君子汤,疗程3周。然后,检测肺功能指标[用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、呼气峰值流速(PEF)]、血气指标[动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)、血氧饱和度(SaO2)]、血清脂质过氧化物(LPO)水平和超氧化物歧化酶(SOD)活性、CAT评分。结果与对照组比较,观察组肺功能指标、PaO2、SaO2、SOD活性显著升高(P<0.05),PaCO2、LPO水平、CAT评分显著降低(P<0.05)。结论丹红六君子汤联合常规治疗可明显改善慢性阻塞性肺疾病患者肺功能、血气水平、生活质量。
AIM To explore the clinical effects of Danhong Liujunzi Decoction combined with routine treatment on patients with chronic obstructive pulmonary disease.METHODS One hundred and twenty patients were randomly assigned into control group(60 cases) for 3-week routine treatment, and observation group(60 cases) for 3-week Danhong Liujunzi Decoction and routine treatment. Subsequently, the changes in lung function indices[forced vital capacity(FVC), forced expiratory volume in the first second(FEV1), peak expiratory flow(PEF)], blood gas indices[arterial partial pressure of oxygen(PaO2), arterial blood carbon dioxide partial pressure(PaCO2), blood oxygen saturation(SaO2)], serum lipid peroxide(LPO) level and superoxide dismutase(SOD) activity, CAT score were detected.RESULTS Compared with the control group, the observation group demonstrated significantly increased lung function indices, PaO2, SaO2, SOD activity(P<0.05), and markedly decreased PaCO2, LPO level, CAT score(P<0.05).CONCLUSION For the patients with chronic obstructive pulmonary disease, Danhong Liujunzi Decoction combined with routine treatment can obviously improve lung functions, blood gas levels and life quality.
作者
李长安
孙思庆
LI Chang-an;SUN Si-qing(Department of Internal Medicine 2, Mingguang Hospital of Traditional Chinese Medicine, Mingguang 239400, China;Department of Respiratory Medicine, Nanjing Thoracic Hospital, Nanjing 210029, China)
出处
《中成药》
CAS
CSCD
北大核心
2019年第7期1561-1564,共4页
Chinese Traditional Patent Medicine
基金
国家中医药管理局基金项目(2014zfyjs009)
关键词
丹红六君子汤
常规治疗
慢性阻塞性肺疾病
Danhong Liujunzi Decoction
routine treatment
chronic obstructive pulmonary disease
