摘要
生物测量在眼科疾病的诊断和治疗中越来越重要,对儿童和青少年的眼轴长度进行监测有助于预防和治疗近视及其引发的眼科疾病,眼轴参数的准确测量也是影响眼病患者术后视觉质量的重要因素。为了测量眼轴参数,本文研究了基于时域低相干技术的眼轴测量方法,研制了高精度、非接触式眼轴测量的原理样机,并开展了相应的实验研究。利用低相干干涉技术与长相干干涉测距技术结合的方法,采用时域的机械扫描方式,搭建一套光纤型低相干层析测量系统。通过对标准透镜厚度和镜面间隔的测量实验,重复测量精度优于0.3μm。最后对鱼眼眼轴参数进行测量,清晰得到鱼眼的角膜、晶状体和视网膜等结构。实验结果表明,该系统的稳定性及重复性均能达到设计要求,可以用于动物眼轴参数的测量。
Biometrics is becoming more and more important in the diagnosis and treatment of ophthalmic diseases. Monitoring the axial length of children and adolescents can help prevent and treat myopia,and the ophthalmic diseases that it causes. The accurate measurement of eye axial parameters is an important factor in visual quality that affects postoperative patients with eye diseases. In order to measure the parameters of the eye axis,the eye axis measurement method based on the time domainlow-coherence technique of time domain is presented. The prototype for high-precision and non-contact measurement is developed and the corresponding experiments are conducted. Using a combination of low-coherence interference technique and long coherent interference ranging technology,a fiber-optic low-coherence tomography measurement system is built using time-domain mechanical scanning. The repeatability error of standard lens thickness and mirror spacing measurements is less than 0.3 μm. In the experimental measurement of fish-eye axis parameters,the structure of the cornea,lens,and retina of the fish eye was clearly tested. The stability and repeatability of the system meets the design requirements. The tomographic measurement experiment on fish eyes successfully verified that the system can be used for the measurement of animal eye axis parameters.
作者
马思齐
巩岩
李丽
张艳微
MA Si-qi;GONG Yan;LI Li;ZHANG Yan-wei(School of Mechatronic Engineering and Automation,Shanghai University,Shanghai 200072,China;Medical Optical Research Laboratory,Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Sciences,Suzhou 215163,China)
出处
《光学精密工程》
EI
CAS
CSCD
北大核心
2019年第6期1318-1326,共9页
Optics and Precision Engineering
基金
国家重点研发计划-高端超分辨显微物镜装配技术联合研究项目(No.2016YFE0110100)
中科院科研装备研制-超分辨物镜一体化装配系统研制项目(No.Y722041202)
关键词
眼轴测量
低相干干涉
相干层析技术
长相干干涉
eye axis measurement
low-coherence interference
coherent tomography
long coherent interference
