摘要
目的 探讨经尿道电切术姑息性治疗伴有膀胱出口梗阻的转移性前列腺癌的临床效果。方法 回顾性分析2015年6月至2016年6月新乡医学院第一附属医院收治的50例伴有膀胱出口梗阻的转移性前列腺癌患者的临床资料,患者均给予经尿道电切术姑息性治疗方案。分别于术前和术后6周对患者行尿流动力学检查、国际前列腺症状评分(I-PSS)及生活质量评分。结果 患者术后6个月的最大尿流率、平均尿流率明显高于术前,残余尿量明显少于术前(P<0.05)。患者术前和术后6个月I-PSS评分分别为20.81±2.30、7.56±1.22,术后6个月的I-PSS评分显著低于术前(t=35.986,P<0.05)。患者术后6个月生活质量各维度得分均显著高于术前(P<0.05)。结论 经尿道电切术姑息性治疗前列腺癌的尿流率改善显著,患者的日常生活质量显著提高。
Objective To investigate the clinical effect of transurethral electrotomy palliative in treatment of metastatic prostate cancer with bladder outlet obstruction.Methods The clinical data of fifty patients with metastatic prostate cancer with bladder outlet obstruction in the First Affiliated Hospital of Xinxiang Medical University from June 2015 to June 2016 were analysed retrospectively.All patients were treated with transurethral electric cutting palliative operation plan and the urodynamics test,international prostate symptom score (I-PSS) and quality of life score were performed before and 6 weeks after operation.Results The maximum urine flow rate,the average urinary flow rate of all patients were significantly more than those before operation(P<0.05);and the residual urine volume was significantly less than that before operation (P<0.05).The I-PSS of patients before and after operation was (20.81±2.30),(7.56±1.22) respectively;the I-PSS after operation was significantly lower than that before operation(P<0.05).The scores of all dimensions of quality of life of patients at 6 months after operation were significantly higher than those before operation (P<0.05).Conclusion Transurethral resection palliative for prostate cancer can significantly improve the urinary flow rate and the quality of life of patients.
作者
余沁楠
薛向东
侯国栋
唐钊
YU Qin-nan;XUE Xiang-dong;HOU Guo-dong;TANG Zhao(Department of Urology,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China)
出处
《新乡医学院学报》
CAS
2019年第7期646-648,共3页
Journal of Xinxiang Medical University
关键词
膀胱出口梗阻
转移性前列腺癌
经尿道电切术
姑息性治疗
bladder outlet obstruction
metastatic prostate cancer
transurethral electrotomy
palliative care