摘要
当归补血汤(DBT)是益气活血的古代经典名方,由当归与黄芪配伍组成,具有补血益气、调节免疫之功效,在临床治疗中具有较高的应用价值,其疗效确切、配伍简单,已成为中药复方研究领域的一个热点研究对象。该文从药理作用、药效物质基础、药代动力学、质量控制、配伍和煎煮工艺方面对DBT的研究现状进行总结与分析,以期为经典名方DBT的开发及质量标准制定提供参考。
Danggui Buxue Tang(DBT) is a famous classical formula of traditional Chinese medicine(TCM) for invigorating Qi and activating blood circulation.It is composed of Angelicae Sinensis Radix and Astragali Radix.It has the effect of enriching blood,invigorating Qi and regulating immunity,and has a high application value in clinical treatment.Because of its definite curative effect and simple compatibility, it has become a hot spot in the research field of TCM.This paper summarized and analyzed the research status of DBT from the pharmacological action, pharmacodynamic material basis, pharmacokinetics, quality control,compatibility and decoction process,so as to provide reference for the development of DBT and formulating its quality standard.
作者
靳如娜
齐晓甜
孙蓉
代云桃
马钊杰
仝家羽
吴红华
JIN Ru-na;QI Xiao-tian;SUN Rong;DAI Yun-tao;MA Zhao-jie;TONG Jia-yu;WU Hong-hua(Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Institute of Advanced Medical Sciences,School of Pharmaceutical Sciences,ShandongUniversity,Jinan 250102,China;The Second Hospital of Shandong University,Jinan 250033,China;Tianjin Key Laboratory of Modern Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China)
出处
《中国实验方剂学杂志》
CAS
CSCD
北大核心
2019年第16期220-228,共9页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金面上项目(81473340)
“泰山学者”建设工程专项(Ns201511107)
国家“重大新药创制”科技重大专项(2009ZX09502-015)
山东省自主创新和成果转化课题(2014ZZCX02104)
关键词
当归补血汤
药理作用
化学成分
药效物质基础
质量控制
经典名方
煎煮工艺
Danggui Buxue Tang
pharmacological action
chemical constituents
pharmacodynamic material basis
quality control
famous classical formulas
decoction process
