摘要
肠易激惹综合征(IBS)主要表现为反复发作的腹痛,可伴有大便形态与频次的改变,是临床消化科医师面临的最常见胃肠道疾病之一。除药物治疗外,饮食干预同样被认为是可取的治疗方式。发酵性寡糖、双糖、单糖及多元醇(FODMAP)是一类不易被小肠吸收的短链碳水化合物,例如果聚糖、低聚半乳糖等。近年世界上很多地区已经考虑将低FODMAP饮食作为IBS的一线治疗方案,但我国相关文献报道较少。本文就近年来低FODMAP饮食干预IBS方面的研究进展作一综述,包括低FODMAP饮食治疗的概念、低FODMAP饮食在IBS患者中的疗效、低FODMAP饮食在IBS患者的实施,其可能的机制,存在的问题及预测疗效的方式。
Irritable bowel syndrome(IBS) is one of the most common functional gastrointestinal diseases in the GI department, manifesting with symptoms including recurrent abdominal pain associated with changes in frequency or form of stools. Besides medication treatments, dietary management has been recommended as an approach. FODMAPs are short chain carbohydrates that are poorly absorbed in the small intestine, including fermentable oligosaccharides, disaccharides and monosaccharides and polyols, such as fructans, galactooligosaccharide, lactose, fructose, xylitol and mannitol. Low FODMAPs diet has been recommended as the first-line approach for treating IBS patients in several countries in recent years. The paper reviews recent progress in low FODMAP diet for treating IBS, including the definition of the low FODMAP diet therapy, its efficacy on the IBS patients, the way how to process it in IBS patients, possible mechanisms, existing problems and the possible ways to predict the efficacy.
作者
金迪
廖欣怡(综述)
刘苓(审校)
JIN Di;LIAO Xinyi(reviewing);LIU Ling(checking)(School of Clinical Medicine, Sichuan University,Chengdu 610041,China;Department of Nutrition, West China Hospital, Sichuan University,Chengdu 610041,China;Department of Gastroenterology and Hepatology, West China Hospital, Sichuan University,Chengdu 610041,China)
出处
《西部医学》
2019年第7期1140-1144,共5页
Medical Journal of West China
基金
四川省重点研发项目资助(2017FZ0047)
