摘要
目的评价莫沙必利联合氟西汀治疗结直肠癌患者术后胃肠功能障碍的效果。方法选取本院2016年3月至2017年3月收治的结直肠癌术后胃肠功能障碍患者80例,采用随机数字表法的分组形式将其平均划分成为实验组与对照组,每组40例。对照组采用莫沙必利治疗措施,实验组在对照组治疗基础上采用氟西汀治疗措施,对比两组治疗效果、胃肠功能恢复状况、外周血胃肠激素指标。结果经治疗,对照组治疗效果低于实验组,两组比较差异具有统计学意义(P<0.05);实验组的胃肠功能恢复指标优于对照组,两组比较差异具有统计学意义(P<0.05);实验组的外周血胃肠激素治疗效果优于对照组,组间对比差异具有统计学意义(P<0.05)。结论在结直肠癌患者术后胃肠功能障碍治疗的过程中,采用莫沙必利联合氟西汀措施能够帮助患者缓解胃肠功能指标,加快恢复速度,具有较高的推广优势。
Objective To evaluate the efficacy of mosapride combined with fluoxetine in the treatment of postoperative gastrointestinal dysfunction in patients with colorectal cancer. Methods 80 patients with postoperative gastrointestinal dysfunction after colorectal cancer admitted to our hospital from March 2016 to March 2017 were randomly divided into experimental group and control group by grouping by random number table. 40 cases in each group. The control group was treated with mosapride, and the experimental group was treated with fluoxetine on the basis of the control group. The therapeutic effects, recovery of gastrointestinal function, and peripheral blood enterosteroids were compared between the two groups. Results After investigation, the treatment effect of the control group was lower than that of the experimental group, and the data of the two groups were statistically significant (P<0.05). The gastrointestinal function recovery index of the experimental group was superior to the control group, and the data of the two groups were statistically significant (P<0.05). The peripheral blood enterosteroid treatment in the control group was worse than the experimental group, and the difference between the two groups was statistically significant. Conclusion In the treatment of postoperative gastrointestinal dysfunction in patients with colorectal cancer, mosapride combined with fluoxetine can help patients to alleviate gastrointestinal function and speed up recovery, and has a higher promotion advantage.
作者
郭昌才
Guo Changcai(Department of General Surgery,Xiajin County People' s Hospital,Dezhou City,Dezhou,Shandong,253200,China)
出处
《当代医学》
2019年第21期56-58,共3页
Contemporary Medicine
关键词
莫沙必利
氟西汀
结直肠癌
术后胃肠功能障碍
Mosapride
Fluoxetine
Colorectal cancer
Postoperative gastrointestinal dysfunction
