摘要
目的探讨艾附暖宫汤剂配合中药外敷治疗原发性痛经的效果及其对患者巨噬细胞移动抑制因子与神经生长因子的影响。方法随机选取2017年6月至2018年6月在本院就诊的原发性痛经患者56例为观察对象,服用艾附暖宫汤治疗,同时配合中药外敷穴位,1个疗程后观察患者治疗前后外周血中巨噬细胞移动抑制因子(MIF)和神经生长因子(NGF)的水平变化,并对患者痛经症状进行评分,评价其治疗前后痛经程度。结果经过1个疗程的治疗,患者MIF和NGF水平分别为(18.45±4.51)ng/ml和(207.62±1.67)pg/ml,均较治疗前明显降低,痛经症状积分也明显降低;56例患者的治愈率为25.0%,有效率为64.3%,总有效率为89.3%。以上差异均有统计学意义(均P<0.05)。结论艾附暖宫汤配合中药外敷可显著降低MIF和NGF水平,具有显著的理气和血,冲任疏通,使经血畅行而止痛的效果。
Objective To explore the effect of Aifunuangong Decoction combined with external traditional Chinese medicine for primary dysmenorrhea and the influence on macrophage migration inhibitory factor (MIF) and nerve growth factor (NGF). Methods From June, 2017 to June, 2018, 56 patients with primary dysmenorrhea were treated with Aifu Nuangong Decoction and external traditional Chinese medicine. At the same time, the changes of MIF and NGF in the patients’ peripheral blood before and after the treatment were observed. The dysmenorrhea symptoms were scored to evaluate the degree of dysmenorrhea before and after the treatment. Results After one course of treatment, the patients’ MIF and NGF were (18.45±4.51)ng/ml and (207.62±1.67) pg/ml, which were significantly lower than those before the treatment. The score of dysmenorrhea symptoms was also significantly lower. The cured rate of the 56 patients was 25.0%;the effective rate was 64.3%;and the total effective rate was 89.3%. The above differences were all with statistical significance (all P < 0.05). Conclusions Aifu Nuangong Decoction combined with external traditional Chinese medicine can significantly reduce the levels of MIF and NGF, have significant effects of regulating qi and blood, and make menstrual blood flow smoothly and relieve pain.
作者
梁平
何冰
Liang Ping;He Bing(Yangjiang Hospital of Traditional Chinese Medicine,Yangjiang 529500,China)
出处
《国际医药卫生导报》
2019年第13期2152-2154,共3页
International Medicine and Health Guidance News
关键词
艾附暖宫汤
中药外敷
原发性痛经
MIF
NGF
Aifu Nuangong Decoction
Traditional Chinese medicine
Primary dysmenorrhea
MIF
NGF
