摘要
目的总结并分析围绝经期女性腰椎1-4、股骨颈及髋关节部位的骨密度(bone mineral density,BMD)及其临床特点。方法收集2017年12月至2018年6月在我院住院部住院并进行双能X线吸收法骨密度检测的183例围绝经期女性,分别测定其腰椎1-4总体BMD、左侧股骨颈及左髋关节全部BMD,同时分析比较年龄、体质量指数(body mass index,BMI)与骨质疏松的关系。结果 183例患者中,检出骨质疏松39例(21.3%),其中腰椎1-4、左股骨颈和左髋关节BMD各检出骨质疏松33例(18.0%)、20例(10.9%)、13例(7.1%)。腰椎总体骨质情况与股骨颈、髋关节检查结果相符的各有129例(70.5%)、119例(65.0%),股骨颈总体骨质情况与髋关节检查结果相符的有137例(74.9%)。在骨质疏松组、骨量减少组和骨量正常组,同一组病人腰椎1-4骨密度>左髋关节骨密度>左侧股骨颈骨密度,组间差异均有统计学意义。年龄、BMI与骨质疏松的发生均相关。骨质疏松与年龄呈正相关,与BMI、腰椎1-4总BMD、左股骨颈BMD、左髋关节BMD负相关,腰椎1-4 BMD与骨质疏松相关程度最高。结论腰椎整体骨密度呈现虚假升高趋势,腰椎1-4 BMD诊断骨质疏松的敏感性和特异性分别为84.6%、100%,股骨颈分别为51.3%、100%,髋关节分别为33.3%、100%;年龄增长、BMI偏低会增加围绝经期妇女罹患骨质疏松的风险。
Objective To summarize and analyze the bone mineral density( BMD) of the lumbar vertebrae 1-4,the femoral neck,and the hip joint,and other clinical features of peri-menopausal women.Methods A total of 183 perimenopausal women who underwent bone mineral density examination with dual-energy X-ray absorptiometry in our hospital from December 2017 to June2018 were collected.BMD of the L1-L4 vertebral body area,the left femoral neck,and the left hip was measured.The relationship among age,body mass index( BMI),and osteoporosis was analyzed.Results Of the 183 patients,39( 21.3%) were found to have osteoporosis.Among them,33 cases( 18.0%),20 cases( 10.9%),and 13 cases( 7.1%) of osteoporosis were found in the lumbar 1-4,the left femoral neck,and the left hip,respectively.The bone status consistency between the total lumbar vertebrae and the femoral neck,the total lumbar vertebrae and the hip bones were 70.5%( 129 cases) and 65%( 119 cases),respectively.The consistency between the femoral neck and the hip was 74.9%( 137 cases).BMD from high to low in the osteoporosis group,the osteopenia group,and the normal bone mass group was at the lumbar vertebrae 1-4,the left hip,and the left femoral neck,and the differences between the groups were statistically significant.Age and BMI were associated with the occurrence of osteoporosis.Osteoporosis was positively correlated with age,but negatively correlated with BMI,BMD of the lumbar vertebrae 1-4,left femoral neck,and left hip.BMD of the lumbar vertebrae 1-4 was most associated with osteoporosis.Conclusion The overall BMD of the lumbar spine shows a false increase trend.The sensitivity and specificity of BMD in the diagnosis of osteoporosis are 84.6% and 100% at the lumbar 1-4,51.3% and 100% at the femoral neck,and 33.3% and 100% at the hip,respectively.The increase in age and decrease in BMI may increase the risk of osteoporosis in perimenopausal women.
作者
刘语涵
李莉
梁德
江晓兵
LIU Yuhan;LI Li;LIANG De;JIANG Xiaobing(The First Clinical Medical College of Guangzhou University of Chinese Medicine,Guangzhou 510405,China;The First Affiliated Hospital of Guangzhou Chinese Medicine University,Guangzhou 510405,China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2019年第7期954-958,共5页
Chinese Journal of Osteoporosis
基金
国家中医临床研究基地业务建设第二批科研专项(JDZX2015078)
关键词
围绝经期
骨密度
骨质疏松
peri-menopause
bone mineral density
osteoporosis
