摘要
目的探讨功能性消化不良(FD)患者采用兰索拉唑联合氟哌噻吨美利曲辛治疗的临床疗效。方法纳入我院2015年7月至2018年6月收治的FD患者共80例,随机分为对照组和观察组各40例。对照组患者采用兰索拉唑肠溶片治疗,观察组患者采用兰索拉唑肠溶片联合氟哌噻吨美利曲辛治疗。比较两组患者的临床疗效及不良反应;随访3个月,比较两组患者的复发率。结果观察组的治疗总有效率为95.00%,显著高于对照组的77.50%(P<0.05)。观察组的不良反应发生率为2.50%,显著低于对照组的17.50%(P<0.05)。观察组的复发率为10.00%,显著低于对照组的37.50%(P<0.05)。结论兰索拉唑联合氟哌噻吨美利曲辛治疗功能性消化不良患者的疗效显著,不良反应发生率和疾病复发率均较低,值得临床推广。
Objective To explore the clinical efficacy of lansoprazole combined with flupenthixol and melitracen in the treatment of patients with functional dyspepsia(PD). Methods A total of 80 FD patients admitted to our hospital from July 2015 to June 2018 were enrolled and randomly divided into control group and observation group, with 40 cases each group. The control group was treated with lansoprazole enteric-coated tablets, while the observation group was treated with lansoprazole enteric-coated tablets combined with flupenthixol and melitracen. The clinical efficacy and adverse reactions of the two groups were compared, and the recurrence rates of the two groups were compared after 3 months of follow-up. Results The total effective rate of observation group was 95.00%, significantly higher than 77.50% of control group(P <0.05). The incidence of adverse reactions of observation group was 2.50%, significantly lower than17.50% of control group(P <0.05). The recurrence rate of observation group was 10.00%, significantly lower than 37.50% of control group(P <0.05). Conclusions Lansoprazole combined with flupenthixol and melitracen in the treatment of patients with functional dyspepsia has significant efficacy, and low incidence of adverse reactions and disease recurrence rate, which is worthy of clinical promotion.
作者
农宇健
NONG Yujian(Second Department of Internal Medicine, Xinyi Hospital of Traditional Chinese Medicine, Xinyi 525300, China)
出处
《临床医学工程》
2019年第8期1117-1118,共2页
Clinical Medicine & Engineering
关键词
功能性消化不良
兰索拉唑
氟哌噻吨美利曲辛
临床疗效
Functional dyspepsia (PD)
Lansoprazole
Flupenthixol and melitracen
Clinical efficacy
