摘要
目的研究探讨阿奇霉素治疗不同类型和不同程度慢性宫颈炎患者的疗效。方法方便选择该院收治的120例慢性宫颈炎患者(2017年1月—2018年12月),所有患者均给予阿奇霉素治疗,根据病变类型分组,分为单纯型糜烂组32例、乳头型糜烂组41例、颗粒型糜烂组47例,再根据病变严重程度分组,分为轻度糜烂组25例、中度糜烂组51例、重度糜烂组44例。比较不同类型、不同程度患者的临床疗效、症状缓解时间、不良反应。结果①单纯型糜烂组的临床总有效率(96.87%)较乳头型糜烂组(78.05%)、颗粒型糜烂组(78.72%)更高(P<0.05),其阴道排液时间(9.27±1.96)d、阴道流血时间(10.06±2.13)d均较乳头型糜烂组、颗粒型糜烂组缩短(P<0.05)。②轻度糜烂组、中度糜烂组的临床总有效率分别为92.00%、92.16%,均较重度糜烂组更高(P<0.05),其各症状缓解时间均较重度糜烂组缩短(P<0.05)。③治疗期间,所有患者均未发生明显不良反应。结论阿奇霉素用于不同类型、不同程度的慢性宫颈炎治疗中,均具有良好的临床疗效和用药安全性。
Objective To investigate the efficacy of azithromycin in the treatment of patients with different types and degrees of chronic cervicitis. Methods 120 patients with chronic cervicitis admitted to our hospital (January 2017 to December 2018) were convenient selected enrolled. All patients were treated with azithromycin. According to the type of lesions, 32 patients were divided into simple erosion group and nipple type erosion group. 47 patients with granular erosion group, and they were divided into 25 cases of mild erosion group, 51 cases of moderate erosion group and 44 cases of severe erosion group according to the severity of lesions. Compare the clinical efficacy, symptom relief time, and adverse reactions of patients with different types and degrees. Results 1.The total clinical effective rate of the simple erosion group (96.87%) was higher than that of the papillary erosion group (78.05%) and the granular erosion group (78.72%)(P<0.05), and the vaginal discharge time (9.27±1.96)d. The time of vaginal bleeding (10.06±2.13)d was shorter than that of the nipple type erosion group and the granular type erosion group (P<0.05). 2.The total clinical effective rate of the mild erosion group and the moderate erosion group were 92.00% and 92.16%, respectively, which were higher than those in the severe erosion group (P<0.05), and the time of symptom relief was shorter than that of the severe erosion group (P<0.05). 3.No significant adverse reactions occurred in all patients during the treatment period. Conclusion Azithromycin has good clinical efficacy and drug safety in the treatment of different types and degrees of chronic cervicitis.
作者
冯双清
陈思斯
廖洁慈
冯文彬
FENG Shuang-qing;CHEN Si-si;LIAO Jie-ci;FENG Wen-bin(Huizhou Second Maternal and Child Health Family Planning Service Center, Huizhou, Guangdong Province, 516001 China)
出处
《中外医疗》
2019年第17期141-143,共3页
China & Foreign Medical Treatment
关键词
慢性宫颈炎
宫颈糜烂
阿奇霉素
病变程度
病变类型
妇产科
Chronic cervicitis
Cervical erosion
Azithromycin
Degree of lesion
Type of lesion
Obstetrics and gynecology
