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蒙古族与汉族患者疼痛敏感性及舒芬太尼术后镇痛效果对比研究 被引量:1

Comparative Study on Pain Sensitivity and Effect of Sufentanil in Postoperative Analgesia Between Mongolian and Han Nationality Patients
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摘要 目的观察蒙古族与汉族患者疼痛敏感性及舒芬太尼术后镇痛效果方面的差异。方法符合纳入标准的蒙古族(M组)和汉族(H组)两组下肢外伤性骨折患者各30例,行择期切开复位内固定手术。术前采用痛阈刺激仪HD-EP601C测定患者的痛阈(PT)和耐痛阈(PTT),评估患者术前、术后疼痛敏感性。术中采用腰硬联合麻醉,术毕采用舒芬太尼术后静脉自控镇痛(PCIA)至术后48h。分别于术前(T1),术后8h(T2)、术后12h(T3)、术后24h(T4)及48h(T5)进行视觉模拟疼痛评分(VAS)。结果两组患者的手术前PT及PTT无显著统计学差异(P>0.05);术后两组患者的PT、PTT均高于术前,且H组明显高于M组(P<0.05);两组患者术前(T1)及术后8h(T2)VAS评分无显著性差异(P>0.05),术后12~48h(T3~T4)存在显著差异(P<0.05),M组VAS评分显著高于H组。结论与汉族患者相比,蒙古族患者术后表现出较强的疼痛敏感性,且术后镇痛药的需求量明显增高,在临床麻醉中术后镇痛用药时应考虑民族差异。 Objective To observe the analgesic effect of differences in pain sensitivity and postoperative sufentanil between Mongolian and Han nationality patients.Methods Patients with lower extremity traumatic fracture in accordance with the inclusion criteria were divided into two groups(n=30):Mongolian group(Group M)and Han group(Group H).The pain threshold stimulator HD-EP601C was used to measure the pain threshold(PT)and pain tolerance threshold(PTT)Preoperatively,to evaluate the sensitivity of patients to pain before and after operation.Use combined spinal and epidural analgesia during the operation,and patient controlled intravenous analgesia(PCIA)with sufentanil for 48 hours after operation. Visual analogue pain score(VAS)was performed before operation(T1),8 hours after operation (T2),12 hours after operation(T3),24 hours after operation(T4)and 48 hours after operation(T5). Results There was no significant difference in PT and PTT before operation between the two groups(P> 0.05).Postoperative PT and PTT in both groups were higher than those before operation,and the PTT in group H was significantly higher than that in group M(P<0.05).There was no significant difference in VAS score before operation(T1)and 8 hours after operation(T2)between the two groups(P>0.05).There was significant difference between12 hours and 48 hours(T3~T4)after operation(P<0.05),and the VAS score of group M was significantly higher than group H.Conclusion Compared with Han patients, Mongolian patients showed stronger pain sensitivity after operation,and the demand for postoperative analgesics increased significantly.Ethnic differences should be taken into account when using analgesics after operation in clinical anesthesia.
作者 张远 窦锡龄 ZHANG Yuan;DOU Xi-ling(International Mongolia hospital of Inner Mongolia,Inner Mongolia Hohhot 010020 China)
出处 《内蒙古医学杂志》 2019年第6期653-655,共3页 Inner Mongolia Medical Journal
基金 2017年度自治区卫生计生科研计划项目(项目编号:201703044)
关键词 蒙古族 疼痛敏感性 术后镇痛 mongolian pain sensitivity postoperative analgesia
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