摘要
纳米材料具有稳定性好、易于合成的特点,在各个领域应用广泛,尤其在适配体生物传感器中应用比较热门,具有增强和放大信号的作用。适配体是一段DNA或RNA序列的单链寡核苷酸,它能够高特异性与多种靶点结合,如细胞、蛋白质、毒素和其他无机或有机分子。该文针对基于纳米材料构建的比色、荧光、电化学、拉曼等4种信号的生物传感器在真菌毒素检测中的应用进行了综述。
Nanomaterials have the characteristics of good stability and easy synthesis. They are widely used in various fields, especially in aptamer biosensors, which have the functions of enhancing signals and amplifying signals. An aptamer is a single-stranded oligonucleotide of a DNA or RNA sequence that binds to a variety of targets with high specificity such as cells, proteins, toxins and other inorganic or organic molecules. This paper reviewed the application of four kinds of signal biosensors based on nanomaterials such as electrochemistry, fluorescence, colorimetric and Raman in mycotoxin detection.
作者
田静
孙文怡
黄宝玺
郭志军
TIAN Jing;SUN Wenyi;HUANG Baoxi;GUO Zhijun(Agricultural College of Yanbian University,Yanji Jilin 133002,China;College of pharmacy,Liaoning University of Traditional Chinese Medicine,Dalian Liaoning 116600,China;Market Supervision Authority of Antu County,Antu Jilin 133600,China)
出处
《延边大学农学学报》
2019年第2期102-109,共8页
Agricultural Science Journal of Yanbian University
基金
吉林省教育厅“十三五”科学技术项目(JJKH20191128KJ)
国家自然科学基金项目(31360384,31460423)
