摘要
目的 探讨不同保温温度对先天性髋关节脱位手术患儿体温与炎症反应的影响。方法 选择我院2017年1月至2018年5月收治的48例先天性髋关节脱位手术患儿作为研究对象,均应用充气式加温毯保温,按保温温度不同等分为A组32℃,B组38℃,C组43℃,观察3组患儿麻醉诱导插管后即刻、手术切皮时、手术开始后1h、手术开始后2h、手术结束时的体温变化;比较3组患儿炎症反应(TGF-β,TNF-α,IL-10,IL-1β)。结果 与麻醉诱导插管后比较,3组患儿各时间点体温均升高至正常范围;同一时间段组间比较,A组麻醉诱导插管时体温低于B,C两组;手术开始1h后,C组患儿体温高于A,B两组;术毕,B组体温高于A,C两组。术后,B组患儿TNF-α,IL-1β较A,C两组明显降低,IL-10,TGF-β明显增高,差异均有统计学意义(P<0.05)。结论 不同的保温温度均对患儿术前以及麻醉诱导过程中低体温有着较好的纠正作用,其中38℃更有利于保证患儿体温平稳,抑制机体炎症反应,益于患儿术后康复。
Objective To investigate the effect of different holding temperatures on body temperature and inflammatory response in children with congenital dislocation of the hip. Methods To select 48 cases of children with congenital dislocation of the hip who were admitted to our hospital from January 2017 to May 2018 as the study subjects. They kept temperature by inflatable blanket. According to the different holding temperatures, these children were divided into group A with the temperature of 32 ℃, group B with the temperature of 38 ℃ and group C with the temperature of 43 ℃. The body temperature changes of children in three groups were observed immediately after anesthesia-induced intubation, at the skin incision, at 1 hour after the surgery, at 2 hours after the surgery, and at the end of the surgery. The inflammatory response(TGF-β,TNF-α,IL-10,IL-1β) of children in the three groups were also compared. Results Compared with the inflammatory response after the anesthesia-induced intubation, the body temperatures of children in three groups increased to the normal range at each time point. Compared with the condition at the same period of time, the body temperatures of group A were lower than that of group B and group C at the time of anesthesia induction. After 1 hour in the surgery, the body temperatures of group C were higher than that of group A and group B. At the end of the surgery, the body temperatures of group B were higher than that of group A and group C. After the surgery, the TNF-α and IL-1β in group B were significantly lower than those in group A and group C. The IL-10 and TGF-β were significantly increased. The differences were statistically significant( P <0.05). Conclusion Different holding temperatures have a good corrective effect on pre-operative and hypothermia during induction of anesthesia. Among the temperatures, the temperature of 38 ℃ is more conducive to ensure that the patient's body temperature is stable. It can inhibit the body's inflammatory response, and is conducive to the postoperative rehabilitation of the children.
作者
陈晶晶
谢馨
CHEN Jing-jing;XIE Xin
出处
《护理实践与研究》
2019年第15期119-121,共3页
Nursing Practice and Research
关键词
先天性髋关节脱位
保温温度
炎症反应
康复效果
Congenital dislocation of the hip
Holding temperatures
Inflammatory response
Rehabilitation effect
