摘要
目的:利用3D分割技术比较增强CT与增强磁共振成像(CE-MRI)对同一肝细胞癌患者肿瘤体积评估的一致性。方法:回顾性收集2014年11月-2018年12月75例在中南大学湘雅二医院首诊且未经历治疗的肝细胞癌患者资料,所有患者均行增强CT和CE-MRI检查,利用区域生长和主动轮廓模型3D病变分割技术,计算两种成像方法所对应的肿瘤体积,并分析其一致性。结果:排除15例由于影像学表现不典型患者,共分析60例患者60个靶病灶(多病灶的病例取最大病灶进行分析)。60例靶病灶在CT增强图像上测量的体积平均值为(22.72±7.49)cm^3,CE-MRI图像上测量的体积平均值为(23.53±7.63)cm^3。两种成像方法测量的肿瘤体积结果比较无统计学意义(t=0.59,P=0.55)。线性回归模型分析结果显示,两种成像方法测量的病灶体积之间具有强相关性(r=0.99,95%CI=0.97~0.99)。结论:运用3D分割技术检测肝细胞癌病灶体积时,增强CT与增强MR图像上所计算出的结果具有高度一致性。
Objective: To compare the consistency between contrast-enhanced CT and contrast-enhanced magnetic resonance imaging(CE-MRI) for determining the volume of tumor in the same patient with hepatocellular carcinoma(HCC) by 3 D segmentation technique. Methods: The data of 60 HCC patients with initial diagnosis in the Second Xiangya Hospital of Central South University without any previous treatment from November 2014 to December 2018 were retrospectively collected. All patients underwent both contrast-enhanced CT scan and CE-MRI examination. The tumor volume corresponding to each imaging examination was calculated by the 3 D lesion segmentation technique using regionbased active and contour model, and then their consistency was analyzed.Results: Fifteen cases were excluded for atypical imaging manifestations, so a total of 60 target lesions in 60 patients were analyzed(the largest lesion was selected in cases with multiple lesions). The mean volume of tumor in the 60 patients measured by enhanced CT was(22.72±7.49) cm^3, by CE-MRI image was(23.53±7.64) cm^3. There was no statistical difference between the two imaging methods in measuring tumor volume(t=0.59, P=0.55). The results of linear regression model showed that there was a strong correlation between the lesion volumes measured by the two imaging methods(r=0.99, 95% CI=0.97–0.99).Conclusion: In determination of the lesion volume of HCC with 3 D segmentation technique, the results obtained by contrast-enhanced CT and CE-MRI are highly consistent.
作者
汤世雄
黎丹
肖恩华
刘佳易
吴雄
卞读军
TANG Shixiong;LI Dan;XIAO Enhua;LIU Jiayi;WU Xiong;BIAN Dujun(Department of Radiology, the Second Xiangya Hospital, Central South University, Changsha 410011, China)
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2019年第7期871-877,共7页
China Journal of General Surgery
基金
湖南省卫计委科研基金资助项目(B2015-0240)
湖南省自然科学基金资助项目(2016JJ4097)
关键词
癌
肝细胞
成像
三维
磁共振成像
体层摄影术
X线计算机
Carcinoma,Hepatocellular
Imaging,Three-Dimensional
Magnetic Resonance Imaging
Tomography,X-Ray Computed
