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慢性支气管炎患儿血清微量元素与免疫指标的关系探讨 被引量:1

Study on the relationship between serum trace elements and immune indexes in children with chronic bronchitis
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摘要 目的探讨慢性支气管炎患儿血清微量元素与免疫指标的关系。方法选取2017年12月至2018年12月我院收治的慢性支气管炎患儿64例设为研究组,另从同期来我院体检的健康儿童中选取60例作为对照组。检测两组的血清微量元素与免疫指标水平,并分析研究组的血清微量元素与免疫指标的相关性。结果研究组的血清Ca、Zn、Fe、IgG及IgA水平均低于对照组(P<0.05);两组血清IgM水平比较,差异无统计学意义(P>0.05)。Pearson相关性分析显示,研究组血清Ca、Zn及Fe水平与IgG、IgA水平呈正相关(P<0.05),血清Ca、Zn、Fe水平均与IgM水平无明显的相关性(P>0.05)。结论慢性支气管炎患儿的血清Ca、Zn、Fe水平与血清IgG、IgA水平呈正相关,在临床的治疗中可适当补充微量元素,改善患儿免疫功能,促进病情的恢复。 Objective To explore the relationship between serum trace elements and immune indexes in children with chronic bronchitis.Methods A total of 64 children with chronic bronchitis admitted in our hospital from December 2017 to December 2018 were selected as research group.Another 60 healthy children had physical examination in our hospital during the same period were selected as control group.The levels of serum trace elements and immune indexes were detected in the two groups,and the relationship between serum trace elements and immune indexes in the research group were analyzed.Results The serum levels of Ca,Zn,Fe,IgG and IgA in the research group were lower than those in the control group(P<0.05).There was no significant difference in serum IgM level between the two groups(P>0.05).Pearson correlation analysis showed that the levels of serum Ca,Zn and Fe were positively correlated with the levels of IgG and IgA(P<0.05),and there was no significant correlation between the levels of serum Ca,Zn and Fe and IgM level(P>0.05).Conclusion The levels of serum Ca,Zn and Fe in children with chronic bronchial diseases are positively correlated with the levels of serum IgG and IgA.In clinical treatment,trace elements can be properly supplemented to improve the immune function of children and promote the recovery of the disease.
作者 曹海丽 CAO Hai-li(Children's Hospital of Kaifeng City,Kaifeng 475000,China)
机构地区 开封市儿童医院
出处 《临床医学研究与实践》 2019年第22期137-138,共2页 Clinical Research and Practice
关键词 慢性支气管炎 微量元素 免疫指标 chronic bronchitis trace elements immune indexes
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