摘要
临床药师参与了3例骨折术后切口愈合不良患者的会诊。对患者实验室数据、临床症状及用药情况分析,提出术后切口愈合不良系低分子肝素钠联合注射用血栓通防治深静脉血栓形成(DVT)引起的出血不良反应所致,经停药、使用止血药均好转出院。现对此病例进行报道,提示低分子肝素钠联合注射用血栓通抗凝效果增强,但药品不良反应发生率也会增加,临床使用中应做好监测工作,提高用药的安全性。
Clinical pharmacists participated in the consultation of 3 patients with poor wound healing after fracture surgery.Based on the analysis of the laboratory data,clinical symptoms and medication of the patients,it was suggested that the poor postoperative wound healing was caused by the combination of low-molecular heparin sodium and Xueshuantong for injection for the prevention and treatment of bleeding adverse reactions caused by DVT.The patients were discharged after the drug withdrawal and haemostatic therapy.The cases were reported in the paper,suggesting that the anticoagulant effect of low-molecular heparin sodium combined with Xueshuantong for injection was enhanced,while the incidence of ADR also increased.Therefore,good monitoring in clinical use should be strengthened in order to improve the safety of medication.
作者
阮芙蓉
张春玲
Ruan Furong;Zhang Chunling(Department of Pharmacy,Xi’an Central Hospital,Xi’an 710003,China;Department of Clinical Pharmacy,Honghui Hospital,College of Medicine,Xi’an Jiaotong University)
出处
《中国药师》
CAS
2019年第8期1486-1489,共4页
China Pharmacist
关键词
低分子肝素钠
血栓通
出血
Low molecular weight heparin sodium injection
Xueshuantong
Hemorrhage
