摘要
本文对薰衣草提取物的抗氧化活性及酶抑制活性(乙酰胆碱酯酶、丁酰胆碱酯酶、酪氨酸酶)进行了研究。采用四种方法(DPPH、FRAP、总抗氧化能力测定、总还原力测定)对液相获得的50个样品进行了抗氧化活性分析,结果表明,26#、27#、35#、36#组分具有较高的抗氧化活性。薰衣草组分对胆碱酯酶抑制活性各不相同,其中16#、18#、19#、20#、24#、37#组分乙酰胆碱酯酶抑制率均大于60%,抑制活性较高;24#、25#、39#、43#、46#丁酰胆碱酯酶抑制率大于20%,抑制活性普遍较低;对酪氨酸酶单/二酚酶抑制活性各不相同,其中16#、17#、18#、19#、20#组分对酪氨酸酶单/二酚酶的抑制活性较高。薰衣草作为药用植物是潜在的生物活性化合物资源,这对人类健康是十分有益的,特别是在筛选天然抗氧化剂和治疗疾病方面。
The antioxidant activity and enzyme inhibitory activities( acetylcholinesterase,butyrylcholinesterase,tyrosinase) of different extracts from Lavandula angustifolia Mill were investigated.The antioxidant activity of 50 simples obtained by HPLC was determined by four methods,namely DPPH,FRAP,total antioxidant capacity and reducing power assay.The results showed that the sample 26 #,27 #,35 #,36 # showed higher antioxidant capacities. All the sample displayed a different degrees of cholinesterase inhibitory.The sample 16 #,18 #,19 #,20 #,24 #,37 # showed higher inhibition rate of acetylcholinesterase( ACHE).The sample 24#,25#,39#,43#,46# showed a low inhibition rate of butyrylcholinesterase( BUCHE).The inhibitory activity of diphenol oxidase in tyrosinase was found significantly higher than those of monophenol oxidase in tyrosinase. The sample 16#,17#,18#,19#,20# showed a high inhibition rate of tyrosinase.Lavandula angustifolia Mill.could provide a potential natural source of bioactive compounds and could be beneficial to the human health,especially in the neurodegenerative disorders and as sources of natural antioxidant in food industry.
作者
王苗苗
严欢
田合
毛琼玲
张倩
李慕春
WANG Miao-miao;YAN Huan;TIAN He;MAO Qiong-ling;ZHANG Qian;LI Mu-chun(Xinjiang Engineering Technology Research Center for Green Processing of Nature Production,Xinjiang Acadenca of Analysis and Testing,Urumqi 830011,China)
出处
《食品工业科技》
CAS
北大核心
2019年第16期14-20,26,共8页
Science and Technology of Food Industry
基金
自治区科技人才培育项目(qn2015jc071)
新疆地产中药民族药新药研发培育项目(2017-02-07)
自治区重点研发计划项目(2017B0316-3)
关键词
薰衣草
抗氧化活性
乙酰胆碱酯酶
丁酰胆碱酯酶
酪氨酸酶
Lavandula angustifolia Mill.
antioxidant activity
acetylcholinesterase
butyrylcholinesterase
tyrosinase
