摘要
目的通过分析襄阳市参加免费孕前优生检查者的实验室结果,探讨孕前优生保健工作开展的重要价值。方法按照国家免费孕前优生健康检查项目技术服务规范,对2016年1月至2017年12月5218例计划怀孕夫妇进行孕前优生健康检查,根据检查结果和评估方法,筛查出高风险人群。结果5218例检查对象经实验室检查共发现高风险人群449人(8.60%),女性高风险因素包括:乙肝感染或携带、肝功能异常、血糖异常、甲状腺功能异常、肾功能异常、巨细胞和弓形虫感染;男性高风险因素依次是肝功能异常、乙肝、肾功能异常;其中30岁以上人群肝肾功能异常、血糖异常、巨细胞病毒和弓形虫感染发生率显著高于30岁以下人群,差异有统计学意义(P<0.05)。结论免费孕前优生检查对优生优育和预防出生缺陷具有十分重要的意义,应加强国家免费孕前优生政策的宣传力度,加大对计划怀孕夫妇的科普宣教工作,减少出生缺陷,提高出生人口素质。
Objective To analyze free pre-pregnancy eugenic health laboratory examination results in Xiangyang city,explore the important value of pre-pregnancy eugenic health examination for eugenics. Methods According to the technical service specification of the national free pre-pregnancy eugenic examination project,a total of 2609 men and 2609 women received free pre-pregnancy eugenic health examination in Xiangyang city from January,2016 to December,2017,then the research objects were screened and selected as the high-risk groups according to examination results and assessment methods. Results A total of 449 cases(8.60%)were selected as high-risk population.Risk factors of women included hepatitis B,liver and renal dysfunction,abnormal blood glucose,thyroid dysfunction,and Cytomegalo virus and Toxplasma infection.Risk factors of men included abnormal liver function,hepatitis B and renal dysfunction.Among them,the incidence of renal dysfunction,abnormal blood glucose and Cytomegalo virus and Toxplasma infection were significantly higher in groups of over 30 years old than groups of under 30( P <0.05). Conclusion Pre-pregnancy eugenic health examination plays an important role in the prevention of birth defects,and the public awareness of pre-pregnancy eugenic health examination should be strengthened.Pre-pregnancy eugenic health examination should be conducted among the couples who is planning for pregnancy to reduce birth defects.
作者
肖玲
岳静
黄光梅
张雪丽
XIAO Ling;YUE Jing;HUANG Guang-mei;ZHANG Xue-li(Department of Gynecology,Xiangyang Maternal and Child Health Hospital,Xiangyang 441021,China;Department of Reproductive Medical Center,Tongji Hospital,Tongji Medical College,Huazhong University of Science & Technology,Wuhan 430030,China)
出处
《标记免疫分析与临床》
CAS
2019年第8期1338-1342,共5页
Labeled Immunoassays and Clinical Medicine
基金
国家重点研发计划(编号:2018YFC1002103)
关键词
孕前优生检查
高风险
实验室检查
结果分析
出生缺陷
Pre-pregnancy eugenic health examination
High risk
Laboratory examination
Results analysis
Birth defect
