摘要
目的:利用超声造影探讨高强度聚焦超声(HIFU)和子宫动脉栓塞(UAE)治疗子宫肌瘤(UF)的疗效差异。方法:选择我院收治的接受HIFU或UAE治疗的UF患者68例(共81个UF)。术前、术后1周、术后3个月、术后6个月时测量UF体积,并通过超声造影观察UF的血流灌注情况。结果:①术后1周时,两组患者UF体积与术前比较,差异无统计学意义(P>0.05);术后3个月、6个月时,两组患者UF体积较术前显著缩小(P<0.05);术前、术后1周、术后3个月及术后6个月时,两组患者UF体积比较,差异无统计学意义(P>0.05)。术后1周、术后3个月及术后6个月,两组患者UF无灌注率差异无统计学意义(P>0.05)。②在最大径≤5cm的49个UF中,两组患者各时间点UF体积比较,差异无统计学意义(P>0.05),各时间点UF无灌注率比较,差异无统计学意义(P>0.05)。③在最大径>5cm的32个UF中,术后6个月时,UAE组UF体积较HIFU组小(P<0.05),术后1周、术后3个月及术后6个月时,UAE组UF无灌注率较HIFU组高(P<0.05)。结论:HIFU和UAE治疗UF均疗效确切,当UF最大径>5cm时,UAE疗效优于HIFU。
Objective:To investigate the difference of high-intensity focused ultrasound(HIFU) and uterine artery embolization( UAE) in the treatment of uterine fibroids(UF) using contrast enhanced ultrasound.Methods:A total of 68 UF patients(81 myomas) who were treated with HIFU or UAE in our hospital were selected.The volume of fibroids were measured before surgery, 1 week after surgery,3 months after surgery,and 6 months after surgery.Theperfusion of fibroids was observed by contrast- enhanced ultrasound.Results:①There was no significant difference ofthe volume of fibroids in the two groups 1 week after operation compared with that before surgery(P>0.05).At,3 months and 6 months after operation,the volume of fibroids in the two groups decreased compared with that before surgery(P<0.05).There was no significant difference in the volume of fibroids between the two groups before operation,1 week after operation,3 months after operation and 6 months after operation (P>0.05).There was no significant difference in the rate of non-perfusion of fibroids between the two groups at 1 week,3 months and 6 months after operation(P>0.05).②Among the 49 UFs with a maximum diameter≤5 cm,there was no significant difference in the volume of fibroids between the two groups at each time point(P>0.05).There was no statistically significant difference in the rate of non-perfusion of fibroids at each time point(P>0.05).③In 32 UFs with a maximum diameter>5 cm,the volume of fibroids in the UAE group was smaller than that in the HIFU group at 6 months after surgery(P<0.05).At 1 week,3 months and 6 months after surgery,the rate of non-perfusion of fibroids in the UAE group was higher than that in the HIFU group(P<0.05).Conclusions:Both HIFU and UAE are effective in treating UF.When UF diameter>5 cm,UAE is more effective than HIFU.
作者
刘政
田锦
张惠
米成嵘
LIU Zheng;TIAN Jin;ZHANG Hui(Ultrasonic Department,General Hospital of Ningxia Medical University,Yinchuan Ningxia 750004,China)
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2019年第8期633-638,共6页
Journal of Practical Obstetrics and Gynecology
关键词
超声造影
高强度聚焦超声
子宫动脉栓塞
子宫肌瘤
疗效差异
Contrast-enhanced ultrasound
High-intensity focused ultrasound
Uterine artery embolization
Uterine fibroids
Difference in curative effect
