摘要
目的分析前庭康复训练联合艾司西酞普兰对慢性主观性头晕(CSD)的近远期疗效及不良反应。方法选取本院在2015年5月~2017年5月月收取的120例慢性主观性头晕患者作为分析对象,按照住院顺序分成对照组和实验组各60例,对照组患者采用艾司西酞普兰药物治疗,而实验组患者在对照组治疗的基础之上增加前庭康复训练,对比两组患者治疗后的指标评分和不良反应。结果治疗后1、2、4周,两组患者的情感、躯体、功能评分及其DHI总分显著低于治疗前,差异有显著性(P<0.05);另外,治疗后1、2、4周,实验组患者的情感、躯体、功能评分及其DHI总分显著低于对照组,差异有显著性(P<0.05);而实验DHI总分及躯体因子分从治疗后2周末开始均明显低于对照组(P<0.05);两周患者的临床不良反应但大多数都是在治疗后两周内,并且程度比较轻(P>0.05).结论针对慢性主观性头晕患者采用前庭康复训练联合艾司西酞普兰药物治疗,效果比较显著,安全性较高,并且不良反应较少,值得临床大力推广应用。
Objective To analyze the short-term and long-term effects of vestibular rehabilitation combined with escitalopram on chronic subjective dizziness(CSD). Methods A total of 120 patients with chronic subjective dizziness in the hospital from May 2015 to May 2017 were enrolled. The patients were divided into the control group and the experimental group according to the hospitalization order.60 patients in the control group were treated with escitalopram treatment,while the experimental group patients increased vestibular rehabilitation training based on the treatment of the control group,comparing the index scores and adverse reactions after treatment. Results At 1,2,and 4 weeks after treatment,the emotional,physical,functional scores and DHI total scores of the two groups were significantly lower than before treatment,and the difference was significant(P<0.05). In addition,1,2 after treatment at 4 weeks,the emotional,physical,functional scores and DHI scores of the experimental group were significantly lower than those of the control group,and the difference was significant(P<0.05). The experimental DHI total score and body factor scores began at 2 weeks after treatment. It was significantly lower than the control group(P<0.05);the clinical adverse reactions of the two weeks were mostly within two weeks after treatment,and the degree was relatively mild(P>0.05). Conclusion The vestibule was used for patients with chronic subjective dizziness. Rehabilitation training combined with escitalopram drug treatment,the effect is more significant,higher safety,and fewer adverse reactions,it is worthy of clinical promotion.
作者
李友梅
冯晓丽
张顺
LI Youmei;FENG Xiaoli;ZHANG Shun(Shanghai Yangpu District Central Hospital,Shanghai 200093,China)
出处
《国际精神病学杂志》
2019年第4期686-689,共4页
Journal Of International Psychiatry
基金
脑卒中三级康复网络建设的前瞻性研究(编号:13411951102)
关键词
前庭康复训练
艾司西酞普兰
慢性主观性头晕
Vestibular rehabilitation training
Escitalopram citalopram
Chronic subjective dizziness