摘要
目的探讨纳洛酮联合无创呼吸机治疗老年慢性阻塞性肺疾病(COPD)并发呼吸衰竭的效果及对患者生命体征的影响。方法回顾性分析2018年6月至2018年12月我院呼吸内科收治的84例老年COPD并发呼吸衰竭患者的临床资料,根据治疗方式的不同将其分为对照组和观察组,各42例。对照组给予常规的临床治疗与无创呼吸机联合治疗,观察组在对照组的治疗基础上予以纳洛酮治疗。比较两组的治疗效果。结果观察组的治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者PaCO2均降低,PaO2与SpO2均升高,且观察组均优于对照组,差异有统计学意义(P<0.05)。治疗后,两组患者HR及RR均降低,且观察组均低于对照组,差异有统计学意义(P<0.05)。结论纳洛酮联合无创呼吸机治疗老年COPD并发呼吸衰竭效果显著,可以有效改善患者的生命体征,值得应用。
Objective To explore the effect of naloxone combined with non-invasive ventilator in elderly patients with chronic obstructive pulmonary disease (COPD) complicated with respiratory failure and its influence on vital signs of patients. Methods The clinical data of 84 elderly patients with COPD complicated with respiratory failure admitted in our hospital from June 2018 to December 2018 were retrospectively analyzed. The patients were divided into control group and observation group according to different treatment methods, with 42 cases in each group. The control group was given routine clinical treatment combined with non-invasive ventilator treatment, while the observation group was given naloxone treatment on the basis of the treatment of the control group. The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the observation group was significantly higher than that in the control group (P<0.05). After treatment, the PaCO2 decreased, the PaO2 and SpO2 increased in both groups, and those in the observation group were better than the control group, the differences were statistically significant (P<0.05). After treatment, the HR and RR in both groups decreased, and those in the observation group were lower than the control group, the differences were statistically significant (P<0.05). Conclusion Naloxone combined with non-invasive ventilator in the treatment of elderly COPD complicated with respiratory failure has a significant effect, which can effectively improve the vital signs of patients and is worth of applying.
作者
杨敏娥
柳胜陇
YANG Min-e;LIU Sheng-long(Respiratory Medicine Department, Changqing Oilfield Staff Hospital,Xi'an 710201, China;Intensive Medicine Department, Changqing Oilfield Staff Hospital,Xi'an 710201, China)
出处
《临床医学研究与实践》
2019年第24期39-41,共3页
Clinical Research and Practice
关键词
无创呼吸机
纳洛酮
慢性阻塞性肺疾病
呼吸衰竭
non-invasive ventilator
naloxone
chronic obstructive pulmonary disease
respiratory failure
