摘要
目的观察氮卓斯汀鼻喷剂联合西替利嗪片治疗过敏性鼻炎的临床效果。方法回顾性分析本院收治的182例过敏性鼻炎患者的病例资料,按照治疗方式的不同将其分为试验组(91例,盐酸氮卓斯汀鼻喷雾剂+西替利嗪片)和对照组(91例,盐酸氮卓斯汀鼻喷雾剂)。比较两组的治疗效果。结果试验组的治疗总有效率显著高于对照组(P<0.05)。治疗后,两组患者的临床症状积分明显低于治疗前,且试验组低于对照组(P<0.05)。两组患者不良反应总发生率无显著差异(P>0.05)。随访3个月,试验组的复发率显著低于对照组(P<0.05)。结论氮卓斯汀鼻喷剂联合西替利嗪片治疗过敏性鼻炎患者的近期效果显著,可以改善患者临床症状及体征,降低复发率。
Objective To observe the clinical effect of azolastine nasal spray combined with cetirizine tablets in the treatment of allergic rhinitis. Methods The clinical data of 182 patients with allergic rhinitis admitted in our hospital were retrospectively analyzed. The patients were divided into experimental group (91 cases, azolastine nasal spray+cetirizine tablets) and control group (91 cases, azolastine nasal spray) according to the different treatment methods. The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the experimental group was significantly higher than that in the control group (P<0.05). After treatment, the scores of clinical symptoms in the two groups were significantly lower than those before treatment, and those in the experimental group were lower than the control group (P<0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05). The recurrence rate in the experimental group was significantly lower than that in the control group (P<0.05). Conclusion Azolastine nasal spray combined with cetirizine tablets in the treatment of allergic rhinitis has a significant short-term effect. It can improve the clinical symptoms and signs of patients and reduce the recurrence rate.
作者
白志刚
李慧
刘峰
杜晓荣
王飞龙
BAI Zhi-gang;LI Hui;LIU Feng;DU Xiao-rong;WANG Fei-long(E.N.T. Department, Yulin No.2 Hospital, Yulin 719000;E.N.T. Department, the People's Hospital of Fugu County,Yulin 719400, China)
出处
《临床医学研究与实践》
2019年第24期113-114,共2页
Clinical Research and Practice
