摘要
目的分析奥司他韦配合小柴胡颗粒治疗小儿流感的效果与预后状况。方法选取2018年1月~2019年1月我院收治的90例流感患儿,随机分成对照组和研究组,每组45例。对照组采用奥司他韦胶囊治疗,研究组在对照组基础上联合小柴胡颗粒治疗。对比两组症状缓解时间、临床疗效及不良反应。结果研究组发热、咳嗽、扁桃体肿大缓解时间分别为(2.05±0.43)d、(3.02±0.93)d、(2.73±0.77)d,短于对照组的(4.31±1.63)d、(4.99±1.62)d、(3.98±1.32)d,差异具有统计意义(P<0.05),而两组鼻塞缓解所用的时间比较,差异无统计学意义(P>0.05)。两组治疗总有效率及不良反应总发生率比较,差异无统计学意义(P>0.05)。结论采用奥司他韦联合小柴胡颗粒治疗小儿流感,能缩短病程,且用药安全性高。
Objective To analyze the effect and prognosis of oseltamivir combined with Xiaochaihu granules in the treatment of childhood flu.Methods 90 children with influenza admitted to our hospital from January 2018 to January 2019 were randomly divided into control group and study group,with 45 cases in each group.The control group was treated with oseltamivir capsules,and the study group was treated with Xiaochaihu granules on the basis of the control group.The time to symptom relief,clinical efficacy and adverse reactions were compared between the two groups.Results The remission time of fever,cough and tonsil swelling in the study group were(2.05±0.43)d,(3.02±0.93)d,(2.73±0.77)d,which was shorter than that of the control group(4.31±1.63)d,(4.99±1.62)d,(3.98±1.32)d,the difference was statistically significant(P<0.05),and there was no significant difference in the time between the two groups of nasal congestion relief(P>0.05).There was no significant difference in the total effective rate and the overall incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of oseltamivir and Xiaochaihu granules in the treatment of pediatric influenza can shorten the course of disease and has high safety.
作者
杨丽微
YANG Li-wei(Department of Pediatrics,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
出处
《医学信息》
2019年第17期161-163,共3页
Journal of Medical Information
关键词
奥司他韦胶囊
小儿流感
小柴胡颗粒
不良反应
预后
Oseltamivir capsule
Pediatric influenza
Xiaochaihu granules
Adverse reactions
Prognosis