摘要
目的对右美托咪啶静脉注射辅助全身麻醉的效果进行分析和研究。方法选择该院在2017年5月-2018年5月期间收治的80例需全身麻醉的患者作为研究对象,按照病历单双号将其划分为对照组和观察组,每组40例。利用生理盐水辅助全身麻醉的方式对对照组进行麻醉,利用右美托咪啶静脉注射辅助全身麻醉的方式对观察组进行麻醉,对两组患者的麻醉效果进行分析和比较。结果对照组麻醉前Ramsay评分为(1.38±0.55)分,麻醉后5min为(1.91±0.51)分,麻醉后15 min为(2.91±0.48)分,观察组麻醉前Ramsay评分为(1.39±0.54)分,麻醉后5 min为(3.49±0.66)分,麻醉后15 min为(4.11±0.52)分。两组患者麻醉前Ramsay评分差异无统计学意义(P>0.05),麻醉后5 min、麻醉后15 min的Ramsay评分均差异有统计学意义(P<0.05)。对照组麻醉后的心率为(96.82±7.01)次/min,舒张压为(94.52±16.29)mmHg,收缩压为(149.55±14.04)mmHg,观察组麻醉后的心率为(74.22±1.53)次/min,舒张压为(73.40±8.27)mmHg,收缩压为(113.82±11.52)mmHg。两组患者的心率、舒张压和收缩压均差异有统计学意义(P<0.05)。对照组不良反应发生率为7.5%,观察组不良反应发生率为5.0%。在不良反应发生率方面两组患者相比差异无统计学意义(χ2=0.338,P>0.05)。结论右美托咪啶静脉注射辅助全身麻醉具有很好的麻醉效果,而且安全性很高,值得在临床上予以进一步推广和应用。
Objective To analyze and study the effect of intravenous dexmedetomidine on general anesthesia. Methods Eighty patients who underwent general anesthesia from May 2017 to May 2018 were enrolled in the study. According to the single or double number of the medical records, they were divided into control group and observation group, with 40 cases in each group. The control group was anesthetized by means of saline-assisted general anesthesia, and the observation group was anesthetized by intravenous injection of dexmedetomidine for general anesthesia. The anesthetic effects of the two groups were analyzed and compared. Results The Ramsay score in the control group was(1.38±0.55)points before the anesthesia,(1.91±0.51)points at 5 minutes after anesthesia, and(2.91±0.48)points at 15 minutes after anesthesia. The Ramsay score in the observation group was(1.39±0.54)points before the anesthesia,(3.49±0.66)points at 5 minutes after anesthesia, and(4.11±0.52)points at 15 minutes after anesthesia. There was no statistically significant difference in Ramsay scores between the two groups before anesthesia(P>0.05), and the Ramsay scores at 5 min after anesthesia and 15 min after anesthesia were statistically significant different(P <0.05). The heart rate of the control group after anesthesia was(96.82±7.01) times/min, diastolic blood pressure was(94.52±16.29) mmHg, systolic blood pressure was(149.55±14.04) mmHg. The heart rate of the observation group after anesthesia was(74.22±1.53) times/min, the diastolic blood pressure was(73.40±8.27) mm Hg, and the systolic blood pressure was(113.82±11.52) mmHg.The difference in the heart rate, diastolic blood pressure, systolic blood pressure was statistically significant(P<0.05).The incidence of adverse reaction was 7.5% in the control group, and 5.0% in the observation group was. There was no statistically significant difference in the incidence of adverse reactions between the two groups(χ2=0.338, P >0.05).Conclusion Dexmedetomidine intravenous injection assisted general anesthesia has good anesthetic effect. Moreover, it is safe and worthy of further promotion and application in clinic.
作者
吴明
WU Ming(Department of Anesthesiology, Dongming County People's Hospital, Dongming, Shandong Province, 274500 China)
出处
《系统医学》
2019年第15期28-30,共3页
Systems Medicine
关键词
全身麻醉
生理盐水
右美托咪啶
静脉注射
效果
General anesthesia
Normal saline
Dexmedetomidine
Intravenous injection
Effect
