摘要
目的:采用Meta分析对穴位注射治疗膝骨关节炎的临床疗效进行评价。方法:电脑检索中国知网(CNKI)、维普(VIP)、万方(WANFANG)、中国生物医学文献数据库(CBM)、Cochrane Library、PubMed、Embase相关文献,采用Cochrane 5.1.0系统评价文献质量,统计学分析采用Revman 5.3及Stata 13.0软件进行分析。结果:纳入18篇文献共1 432例患者。结果显示:治疗组在总有效率(OR=3.23,95%CI[2.24,4.65])、改善患者VAS评分(SMD=0.96,95%CI[0.26,1.66])和Lysholm膝关节评分(SMD=-1.85,95%CI[-2.74,-0.96])方面均优于对照组,差异具有统计学意义(P<0.01)。结论:穴位注射治疗KOA具有较好的疗效,但鉴于纳入研究文献的方法学质量较低,仍需更多高质量的对照试验来支持本研究结果。
Objective:To assess the clinical curative effect of acupoint injection for the treatment of knee osteoarthritis by Meta-analysis.Methods:The related literatures on the treatment of knee osteoarthritis were retrieved from CNKI,VIP,Wan-fang,CBM,Cochrane Library,PubMed and Embase.The methodological quality was assessed by Cochrane5.1.0,and statistical analysis was performed by using Revman5.3 and Stata13.0 software.Results:A total of 18 RCT/CCT involving 1432 cases were included.The treatment group had higher effective rate than the control group(OR=3.23,95%CI[2.24,4.65],P<0.01);improving the VAS score(SMD=0.96,95%CI[0.26,1.66],P<0.01)and Lysholm knee score(SMD=-1.85,95%CI[-2.74,-0.96],P<0.01)than the control group,the difference was statistically significant.Conclusion:Acupoint injection exerts certain therapeutic effect for the treatment of knee osteoarthritis.However,due to the low quality of the included studies,more high-quality clinical studies are needed to validate the results.
作者
王青云
郭婷
敬娜
许光明
陈劼
Wang Qingyun;Guo Ting;Jing Na;Xu Guangming;Chen Jie(Clinical Medical School of Acupuncture-Moxibustion and Rehabilitation,Guangzhou Univers让y of Chinese Medicine,Guangzhou 510405 ,China;Shenzhen Pingle Orthopedics Hospital,Shenzhen 518010,China)
出处
《亚太传统医药》
2019年第8期158-164,共7页
Asia-Pacific Traditional Medicine
基金
广东省中医药局科研项目(20171023)
