摘要
目的:对以穴位埋线为主的中医治法治疗黄褐斑的临床研究进行系统评价与Meta分析,试图探讨穴位埋线疗法对黄褐斑的临床疗效。方法:电脑检索PubMed、CochraneLibrary、中国期刊全文数据库(CNKI)、维普(VIP)、万方(WANFANG)等数据库。搜索从当前的时间2018年10月追溯至建库,集合各大数据库里所收录的相关RCT/CCT试验,利用Cochrane5.1.0提供的循证医学届权威的评估标准,对最终纳入的文献进行客观严谨的质量评价与风险评估,再使用Revman5.3软件对穴位埋线为主治疗黄褐斑的有效率、症状积分进行统计分析。结果:总计纳入10篇文献,Meta结果显示:穴位埋线为主组治疗黄褐斑有效率优于常规西药组(OR=5.15,95%CI[3.56,7.45],P<0.01);患者症状积分改善方面,穴位埋线为主组对黄褐斑症状改善程度优于常规西药组(SMD=0.68,95%CI[0.44,0.91],P<0.01)。结论:在有效率、症状改善方面,穴位埋线为主组疗效肯定。
Objective: To systematically evaluate the clinical studies and carry out meta-analysis on acupoint catgut embedding in treating chloasma, thus to explore the clinical effect of acupoint embedding for chloasma. Methods: Relative literatures of RCT/CCT(from the creation of Database to Oct. 2018)were collected from the databases of Cochrane Library, PubMed, Library, CNKI, VIP and WANFANG, quality evaluation and risk assessment of the included studies were conducted using the standards provided by Cochrane5.1.0, and the efficiency and symptom scores of acupoint catgut embedding as the primary treatment for chloasma were statistically analyzed by using Revman5.3 software. Results: A total of 10 literatures were included, and the meta results showed that the effective rate of acupoint catgut embedding was superior to the conventional western medication in the treatment of chloasma(OR=5.15, 95%CI [3.56, 7.45], P <0.01). In terms of the improvement of symptom scores, acupoint catgut embedding group was better than the conventional western medication group(SMD=0.68, 95%CI [0.44, 0.91], P <0.01). Conclusion: Acupoint catgut embedding is effective for chloasma in terms of efficiency and symptom improvement.
作者
骆建宇
冯淑兰
李光耀
LUO Jianyu;FENG Shulan;LI Guangyao(Clinical Medicine College of Acupuncture&Moxibustion and Rehabilitation, Guangzhou University ofChinese Medicine, Guangzhou 510006, China)
出处
《针灸临床杂志》
2019年第9期57-61,共5页
Journal of Clinical Acupuncture and Moxibustion
基金
国家自然科学基金项目,编号:81473756
关键词
黄褐斑
埋线
系统评价
META分析
Chloasma
Acupoint catgut embedding
Systematic evaluation
Meta analysis
