摘要
目的探明不同剂量的阿托伐他汀钙治疗急性心肌梗死患者的临床意义和应用价值。方法方便选取该院2017年10月-2018年10月期间收治的急性心肌梗死患者94例,随机分为研究组和对照组,分别给予40 mg/d、20 mg/d阿托伐他汀钙治疗。观察比较临床指标差异。结果研究组患者治疗后TG、TC、HDL-C、hs-CRP、IL-6分别为:[(1.4±0.3)mmol/L、(3.2±0.4)mmol/L、(1.6±0.2)mmol/L、(3.1±0.7)mg/mL、(132.4±25.1)pg/mL,均显著优于对照组,差异有统计学意义(t=13.143、13.633、15.378、17.434、15.357,P<0.05);研究组患者治疗后IVST、LVDD、LVEF分别为:(11.4±1.9)mm、(46.9±3.5)mm、(59.3±3.4)%均显著优于对照组,差异有统计学意义(t=14.754、14.225、17.322,P<0.05);研究组患者治疗总有效率为91.49%,显著高于对照组(χ^2=9.083,P=0.003<0.05)。结论 40 mg/d的阿托伐他汀钙对急性心肌梗死的治疗后,心脏功能恢复较好,治疗效果较好,值得在临床上推广。
Objective To investigate the clinical significance and application value of different doses of atorvastatin calcium in the treatment of patients with acute myocardial infarction.Methods Convenient select a total of 94 patients with acute myocardial infarction admitted to our hospital from October 2017 to October 2018 were randomly divided into study group and control group,and treated with 40 mg/d and 20 mg/d atorvastatin calcium.Observe and compare the differences in clinical indicators.Results The TG,TC,HDL-C,hs-CRP and IL-6 in the study group were (1.4±0.3)mmol/L,(3.2±0.4)mmol/L,(1.6±0.2)mmol/L,(3.1±0.7)mg/L,(132.4±25.1)pg/mL,respectively,which were significantly better than the control group.The differences were statistically significant(t=13.143,13.633,15.378,17.434,15.357,P<0.05).The IVST,LVDD,and LVEF of the study group were (11.4±1.9)mm,(46.9±3.5)mm,and (59.3±3.4)%,respectively,which were significantly better than the control group(t=14.754,14.225,17.322,P<0.05);the total effective rate of the study group was 91.49%,significantly higher than the control group(χ^2=9.083,P=0.003<0.05).Conclusion After treatment with 40 mg/d atorvastatin calcium for acute myocardial infarction,cardiac function recovery is better and the treatment effect is better.It is worthy of clinical promotion.
作者
吴文建
凌宗攀
WU Wen-jian;LING Zong-pan(Department of Cardiology,Linyi High-tech Hospital,Linyi,Shandong Province,276000 China)
出处
《中外医疗》
2019年第23期102-104,共3页
China & Foreign Medical Treatment
关键词
不同剂量
阿托伐他汀钙
急性心肌梗死
Different doses
Atorvastatin calcium
Acute myocardial infarction
