摘要
金属硫蛋白是一类存在于生物中低分子量,富含半胱氨酸、不含芳香氨基酸的金属结合蛋白质。对金属硫蛋白的结构、4种类型,以及其重金属解毒、清除自由基、氧化应激等功能和开发利用进行了简要概述,对金属硫蛋白在各种疾病方面的研究进行介绍,同时对金属硫蛋白的开发利用进行了展望。
Metalllothionein is a kind of metal-bound protein with low molecular weight,rich in cysteine and no aromatic amino acids. In this paper,the structure,four types of metallothionein,its functions of heavy metal detoxification,free radical scavenging,oxidative stress and its development and utilization were briefly reviewed. The research of metallothionein in various diseases was emphatically introduced. Finally,the developmen and utilization of metallothionein were prospected.
作者
何婧雯
熊海容
王靖
覃瑞
赵平
HE Jingwen;XIONG Hairong;WANG Jing;QIN Rui;ZHAO Ping(College of Life Sciences,South-central University for Nationalities,Wuhan,Hubei 430074,China;Institute of Food and Nutrition Development,Ministry of Agriculture,Beijing 100081,China)
出处
《农产品加工》
2019年第17期72-75,共4页
Farm Products Processing
基金
中南民族大学校级教学改革研究项目:“十二五”国家级中南民族大学民族药学实验教学中心建设项目(JYX18048)
关键词
金属硫蛋白
氧化应激
重金属解毒
疾病
开发利用
metallothionein
oxidativestress
heavymetaldetoxification
diseases
development and utilization