摘要
目的分析我国孕早期妇女慢性病患病现状及其影响因素,为孕前保健、健康宣教及开展疾病筛查提供参考依据。方法对中国孕产妇队列研究·协和项目在2017年7月25日至2018年7月24日招募的孕早期妇女进行一般情况和疾病史的调查,最终获得6916份有效问卷进行统计分析。采用SPSS20.0软件进行统计分析。计数资料组间比较采用χ^2检验或Fisher确切概率法。对于孕妇慢性病患病率的影响因素分析,采用单因素二分类logistic回归和多因素二分类logistic回归分别进行单因素和多因素分析。结果孕早期妇女慢性病自报患病率为6.30%,自报率最高的疾病是甲状腺功能减退症(2.56%),其次是贫血(1.19%)、糖尿病(0.95%)、高血压(0.94%)、甲状腺功能亢进症(0.40%)、心脏病(0.23%)、高血脂(0.13%)。单因素分析结果显示,孕前BMI≥28.0kg/m^2(OR=2.02,95%CI:1.45~2.81)和生活在西部地区(OR=1.51,95%CI:1.18~1.93)是患慢性病的危险因素,生活在南方(OR=0.48,95%CI:0.39~0.60)是患慢性病的保护因素,均有统计学意义(P<0.01)。多因素分析结果发现,孕前BMI≥28.0kg/m^2(OR=1.95,95%CI:1.40~2.72)、生活在西部地区(OR=1.51,95%CI:1.18~1.94)是患慢性病的危险因素,而生活在南方(OR=0.47,95%CI:0.37~0.58)是患慢性病的保护因素,均有统计学意义(P<0.01)。结论我国孕早期妇女慢性病患病现状不容乐观,且影响因素众多;相关部门和妇幼保健人员应开展针对性的健康宣教,调整疾病筛查策略,针对高危人群开展重点筛查。
Objective To analyze the prevalence and influence factors of chronic diseases in 6 916 early pregnant women of China,and to provide the evidences for pre-pregnancy care,health education and disease screening.Methods Women with early pregnancy were from the Chinese Pregnant Women Cohort Study (CPWCS) between July 25th of 2017 and July 24th of 2018.The investigation of general condition and disease history was performed,and eventually 6 916 valid questionnaires were received for statistical analysis.The χ^2 test and fisher exact probability test were used to analyze the data.Univariate binary logistic regression and multivariate binary logistic regression were used for univariate and multivariate analysis,respectively.The used software was SPSS 20.0.Results The self-reported morbidity of chronic diseases in women with early pregnancy was 6.30%,the order of morbidities was hypothyroidism (2.56%),anemia (1.19%),diabetes (0.95%),hypertension (0.94%),hyperthyroidism (0.40%), heart diseases (0.23%) and hyperlipidemia (0.13%).Results of univariate logistic regression showed that that pre- pregnancy BMI≥28 kg/m^2 (OR=2.02,95% CI:1.45-2.81) and living in the west part of China (OR=1.51,95%CI:1.18-1.93) were the risk factors for chronic diseases,the living in the south part of China (OR=0.48,95%CI:0.39-0.60) was a protective factor for chronic disease (P<0.01).The multivariate analysis showed that pre-pregnancy BMI≥28 kg/m^2 (OR=1.95,95%CI:1.40-2.72) and living in the west part of China (OR=1.51,95%CI:1.18-1.94) were the risk factors for chronic diseases,living in the south part of China (OR=0.47,95%CI:0.37-0.58) was a protective factor for chronic disease (P<0.01).Conclusion The prevalence of chronic diseases in women with early pregnancy of China is serious and the influence factors are various.Therefore,the relevant departments and maternal and child health personnel should conduct the health education for pregnant women.They should also adjust disease screening strategies and conduct screening for high-risk population.
作者
湛永乐
石英杰
陈云利
王雅文
蔡姝雅
吴散散
冯雅慧
沈忠周
马帅
马良坤
江宇
ZHAN Yong-le;SHI Ying-jie;CHEN Yun-li;WANG Ya-wen;CAI Shu-ya;WU San-san;FENG Ya-hui;SHEN Zhong-zhou;MA Shuai;MA Liang-kun;JIANG Yu(School of Public Health,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)
出处
《中国慢性病预防与控制》
CAS
CSCD
北大核心
2019年第8期565-569,574,共6页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
中国医学科学院医学与健康科技创新工程(2016-I2M-1-008)
北京市科委首都临床特色应用研究(Z161100000516117)
关键词
孕妇
慢性病
现状
影响因素
Pregnant women
Chronic diseases
Prevalence
Influence factors
