摘要
目的探讨急性有机磷农药中毒患者预后的影响因素。方法回顾性分析2006年1月至2014年12月我院肾内科应用血液净化救治的急性有机磷农药中毒患者116例,按照治疗效果分为死亡组(n=35)和存活组(n=81),对其所收集的临床和实验室资料比较其差异性,并作多因素分析,建立回归模型,且应用ROC曲线分析该模型对预后的评估价值。结果死亡组年龄较大,合并基础病较多,文化程度低,应用组合式血液净化的概率较高,APACHEⅡ评分较高,住院时间短,与存活组比较差异有统计学意义(P<0.05),多因素分析显示,APACHEⅡ评分、住院时间是影响急性有机磷农药中毒预后的独立危险因素(P<0.05),模型AUC面积0.995,灵敏度0.911,特异度0.962。结论APACHEⅡ评分及住院时间可应用于急性有机磷农药中毒的预后评估。
Objective To investigate the influencing factors of prognosis in patients with acute organophosphorus pesticide poisoning. Methods A retrospective analysis was carried out on 116 patients with acute organophosphorus pesticide poisoning treated with blood purification from January 2006 to December 2014 in our hospital.The patients were divided into death group( n =35) and survival group( n =81) according to the treatment effect.The clinical and experimental results were compared,and multivariate analysis was performed to establish a regression model.The ROC curve was used to analyze the prognostic value of the model. Results The patients of death group were older,had more basic diseases,lower education level,higher probability of applying combined blood purification,higher APACHE Ⅱ score,shorter hospital stay,compared with the survival group ( P < 0.05 ).Multivariate analysis showed that APACHE Ⅱ score and hospital stay time were independent risk factors for the prognosis of acute organophosphorus pesticide poisoning ( P < 0.05 ).The model AUC area was 0.995,the sensitivity was 0.911,and the specificity was 0.962. Conclusion APACHE Ⅱ score and hospital stay can be used to evaluate the prognosis of acute organophosphorus pesticide poisoning.
作者
陈天浩
黄正
Chen Tianhao;Huang Zheng(Department of Nephrology,Tianchang People's Hospital,Tianchang 239300,China;Department of Oncology,Tianchang People's Hospital,Tianchang 239300,China)
出处
《临床荟萃》
CAS
2019年第8期744-747,共4页
Clinical Focus
关键词
有机磷化合物
杀虫剂中毒
预后
organophosphorus compounds
pesticide poisoning
prognosis
