摘要
目的:探讨安胎方加味治疗早期先兆流产合并宫腔积血的临床疗效。方法:选取2017年11月至2018年12月清远市中医院收治的早期先兆流产合并宫腔积血患者120例,随机分为观察组和对照组,每组60例。对照组患者给予黄体酮联合间苯三酚治疗,观察组患者在对照组的基础上加用安胎方加味治疗。观察两组患者的临床疗效,中医症候积分,人绒毛膜促性腺激素β亚单位(β-HCG)、雌激素(E2)及孕酮(P)水平,NT结果和新生儿情况。结果:观察组患者的总有效率为91.67%(55/60),明显优于对照组的78.33%(47/60),差异有统计学意义(P<0.05);治疗后,观察组患者的阴道出血、小腹坠胀疼痛、腰部酸痛及膝软乏力的中医症候积分明显优于对照组,差异均有统计学意义(P<0.05);治疗后,两组患者的β-HCG、E2及P水平明显高于治疗前,且观察组患者明显高于对照组,差异均有统计学意义(P<0.05);观察组患者的NT结果正常率为98.33%(59/60),对照组为95.00%(57/60),两组的差异无统计学意义(P>0.05);且两组均无新生儿畸形、死亡病例。结论:安胎方加味治疗早期先兆流产合并宫腔积血的疗效显著,可缓解患者症状,有效减少宫腔积血与阴道出血,且使机体各项激素处于相对平衡的状态。
OBJECTIVE:To probe into the clinical efficacy of modified prescription for miscarriage prevention in treatment of early threatened abortion complicated with intrauterine hematocele.METHODS:120 patients with early threatened abortion complicated with intrauterine hematocele admitted into Qingyuan Hospital of Traditional Chinese Medicine from Nov.2017 to Dec.2018 were selected and divided into observation group and control group via random number table,with 60 cases in each group.The control group was given progesterone combined with phloroglucinol,while the observation group was treated with modified prescription for miscarriage prevention based on the control group.The clinical efficacy,TCM syndrome scores,levels of β-HCG,E2 and P,NT results and neonatal condition of the two groups were observed.RESULTS:The total effective rate of observation group was 91.67%(55/60),which was significantly better than that of the control group (78.33%,47/60),with statistically significant difference ( P <0.05);after treatment,TCM syndrome scores of colporrhagia,bearing-down and swelling pain of lower abdomen,aching pain of waist and knee weakness of observation group were significantly better than those of the control group,with statistically significant differences ( P <0.05);after treatment,the β-HCG,E2 and P levels of both groups had been significantly increased,and those of the observation group were significantly higher than the control group,with statistically significant differences ( P <0.05);the normal rate of NT results of observation group was 98.33%(59/60),that of the control group was 95.00%(57/60),with no statistically significant difference ( P >0.05);there were no neonatal deformity and morality in both group.CONCLUSIONS:The efficacy of modified prescription for miscarriage prevention in treatment of early threatened abortion complicated with intrauterine hematocele is remarkable,which can relieve patients’ symptoms,effectively reduce intrauterine hematocele and colporrhagia,remain the body’s hormones in a relatively balanced state.
作者
由春玲
谢洁洁
YOU Chunling;XIE Jiejie(Dept.of Gynecology,Qingyuan Hospital of Traditional Chinese Medicine,Guangdong Qingyuan 511500,China)
出处
《中国医院用药评价与分析》
2019年第9期1095-1097,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
基金
清远市科学技术局课题(No.170808191901164)
关键词
安胎方加味
早期先兆流产合并宫腔积血
临床疗效
观察
Modified prescription for miscarriage prevention
Early threatened abortion complicated with intrauterine hematocele
Clinical efficacy
Observation
