摘要
目的:探讨参附注射液联合阿司匹林、氯吡格雷治疗急性心肌梗死的疗效。方法:选取2017年6月至2018年6月西安交通大学第二附属医院收治的急性心肌梗死患者160例,以随机数字表法分为对照组与观察组,每组80例。对照组患者给予阿司匹林联合氯吡格雷治疗,观察组患者在对照组基础上加用参附注射液。观察两组患者的临床治疗效果(包括临床症状疗效与心电图疗效),记录患者的病死情况。结果:观察组患者的临床症状总有效率为90.0%(72/80),明显高于对照组的57.5%(46/80),差异有统计学意义(P<0.05);观察组患者的心电图总有效率为82.5%(66/80),明显高于对照组的52.5%(42/80),差异有统计学意义(P<0.05);观察组患者的病死率为10.0%(8/80),明显低于对照组的37.5%(30/80),差异有统计学意义(P<0.05)。结论:参附注射液联合阿司匹林、氯吡格雷治疗急性心肌梗死的疗效显著,可提高患者生存率。
OBJECTIVE: To probe into the efficacy of Shenfu injection combined with aspirin and clopidogrel in treatment of acute myocardial infarction. METHODS: 160 patients with acute myocardial infarction admitted into the Second Affiliated Hospital of Xi’an Jiaotong University from Jun. 2017 to Jun. 2018 were selected and divided into control group and observation group via random number table, with 80 cases in each group. The control group was given aspirin combined with clopidogrel, while the observation group wastreated with Shenfu injection based on the control group. The clinical therapeutic effect(including clinical symptoms and ECG efficacy) of both groups were observed, patients’ death was recorded. RESULTS: The total effective rate of observation group was 90.0%(72/80), which was significantly higher than that of the control group(57.5%, 46/80), with statistically significant difference(P<0.05);the ECG effective rate of observation group was 82.5%(66/80), which was significantly higher than that of the control group(52.5%, 42/80), with statistically significant difference(P<0.05);the death rate of observation group was 10.0%(8/80), which was significantly lower than that of the control group(37.5%, 30/80), with statistically significant difference(P<0.05). CONCLUSIONS: The efficacy of Shenfu injection combined with aspirin and clopidogrel in treatment of acute myocardial infarction is remarkable, which can improve patients’ survival rates.
作者
朱参战
王新宏
刘昕
薛嘉虹
赵玲
宋雅璠
周甜
张明娟
ZHU Canzhan;WANG Xinhong;LIU Xin;XUE Jiahong;ZHAO Ling;SONG Yafan;ZHOU Tian;ZHANG Mingjuan(Dept.of Cardiology, the Second Affiliated Hospital of Xi' an Jiaotong University, Shaanxs Xi' an 710004, China)
出处
《中国医院用药评价与分析》
2019年第8期950-952,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
