摘要
目的对小剂量缩宫素联合前列腺素类药物对高危产妇剖宫产产后出血的效果进行分析和介绍。方法选择该院在2017年6月—2018年6月期间收治的150例实施剖宫产手术的高危产妇作为研究对象,按照病历单双号将其划分为对照组和观察组,每组75例,采用缩宫素对对照组产妇进行治疗,采用卡前列素氨丁三醇联合缩宫素对观察组产妇进行治疗,对两组产妇的产后出血量、产后出血发生率和不良反应发生率进行比较。结果对照组产妇中共计有19例产后出血,达到了25.3%的出血率,观察组产妇中共计有4例产后出血,达到了5.3%的出血率。在出血率方面两组产妇相比差异有统计学意义(P<0.05)。对照组产妇产后2 h达到了(351.2±54.7)mL的出血量,产后24 h达到了(491.8±54.8)mL的出血量,观察组产妇产后2 h达到了(198.5±27.3)mL的出血量,产后24 h达到了(288.4±40.7)mL的出血量。在产后2 h、产后24 h方面两组产妇相比差异有统计学意义(P<0.05)。两组产妇均未出现严重的不良反应,其中对照组中有2例腹泻,2例发热和1例恶心呕吐,占6.7%,观察组中有2例皮疹,1例心跳加速和2例恶心呕吐,占6.7%,两组相比差异无统计学意义(χ^2=0.000,P>0.05)。在没有经过处理的情况下两组产妇的不良反应均在不久后消失。结论卡前列素氨丁三醇联合缩宫素就可以极大的降低高危产妇剖宫产产后出血发生率,而且安全性很高,值得在临床上予以进一步的推广和应用。
Objective To analyze and introduce the effect of low-dose oxytocin combined with prostaglandins on postpartum hemorrhage in high-risk women with cesarean section. Methods A total of 150 high-risk women undergoing cesarean section who were admitted to our hospital from June 2017 to June 2018 were selected as the study subjects. The patients were divided into the control group and the observation group according to the medical records. 75 patients were treated with oxytocin for the control group. The patients in the observation group were treated with carprostol tromethamine combined with oxytocin. The postpartum hemorrhage, postpartum hemorrhage rate and adverse reactions occurrance rate in the two groups were compared. Results There were 19 postpartum hemorrhages in the control group, which reached 25.3% bleeding rate. There were 4 postpartum hemorrhages in the observation group, which reached 5.3% bleeding rate. There was a significant difference in the bleeding rate between the two groups (P<0.05). The control group reached a (351.2±54.7)mL of bleeding 2 hours after delivery, and reached (491.8±54.8)mL of bleeding 24 hours after delivery. The observation group reached a (198.5±27.3)mL of bleeding 2 hours after delivery. The amount of bleeding(288.4±40.7)mL was reached 24 hours after birth. There were significant differences between the two groups at 2 hours postpartum and 24 hours postpartum, which was statistically significant (P<0.05). There were no serious adverse reactions in the two groups, including 2 cases of diarrhea in the control group, 2 cases of fever and 1 case of nausea and vomiting, accounting for 6.7%. There were 2 cases of rash in the observation group, 1 case of heartbeat acceleration and 2 cases of nausea and vomiting, accounting for 6.7%, the difference was not significant between the two groups (χ^2 =0.000, P>0.05). In the absence of treatment, the adverse reactions of the two groups of women disappeared soon. Conclusion Carbaryl tromethamine combined with oxytocin can greatly reduce the incidence of postpartum hemorrhage in high-risk women with cesarean section, and it is safe and worthy of further promotion and application in clinical practice.
作者
苏燕敏
SU Yan-min(Department of Obstetrics and Gynecology, People's Hospital of Sishui County, Sishui, Shandong Province, 273200 China)
出处
《系统医学》
2019年第16期114-116,共3页
Systems Medicine
