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胞磷胆碱联合美金刚治疗血管性痴呆的临床效果

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摘要 目的观察胞磷胆碱联合美金刚治疗血管性痴呆(VD)的临床效果。方法将2017年1月至2018年3月沈丘县中医院收治的92例VD患者采用随机数表法分为A、B两组,每组46例。A组患者接受美金刚治疗,B组患者加服胞磷胆碱。对比两组患者治疗前后简易智力状态检查量表(MMSE)和日常生活活动能力量表(ADL)评分,检测两组患者治疗前后血清C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平,统计两组患者治疗总有效率。结果治疗后,B组患者MMSE评分和ADL评分均高于A组,血清CRP、TNF-α水平均低于A组,差异有统计学意义(均P<0.05)。A组和B组治疗总有效率分别为80.43%(37/46)、95.65%(44/46),B组治疗总有效率高于A组,差异有统计学意义(P<0.05)。结论胞磷胆碱联合美金刚治疗VD临床疗效较好,可有效改善患者认知功能和自主生活能力,降低体内炎症水平。
作者 王彦
出处 《河南医学研究》 CAS 2019年第19期3559-3560,共2页 Henan Medical Research
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