摘要
目的分析支气管扩张合并感染患者采取支气管镜下肺泡灌洗治疗的效果及对呼吸功能、炎性因子的作用。方法此次选择2015年1月—2018年12月该院收治支气管扩张合并感染患者80例为研究目标。参照计算机抽选结果分为观察组与对照组,对照组患者均接受常规治疗,观察组患者在此基础上采取支气管镜下肺泡灌洗治疗,对比临床效果,统计并分析各组患者治疗前后呼吸功能指标、炎性因子指标差异。结果观察组患者治疗总有效率97.50%明显优于对照组(χ^2=7.31,P<0.05)。经治疗后,观察组患者血氧分压(92.04±1.15)mmHg、氧合指数(376.49±10.38)均明显高于对照组,二氧化碳分压(35.02±1.03)mmHg低于对照组(t=16.27、10.48、11.58,P<0.05)。观察组患者肿瘤坏死因子α(11.47±1.03)pg/mL、白介素-8(99.58±1.04)pg/mL、C反应蛋白(35.99±1.32)mg/L较对照组相比更低(t=10.38、20.41、21.48,P<0.05)。结论支气管扩张合并感染患者采取支气管镜下肺泡灌洗治疗效果更佳,能够改善患者呼吸功能,降低炎性因子水平,值得临床应用。
Objective To analyze the effect of bronchoscopy on alveolar lavage in patients with bronchiectasis and infection and its effects on respiratory function and inflammatory factors.Methods 80 patients with bronchial dilatation and infection were enrolled in the hospital from January 2015 to December 2018.According to the results of computer sampling,the patients were divided into observation group and control group.The patients in the control group received routine treatment.The patients in the observation group were treated with bronchoscopy under the condition of laparoscopic alveolar lavage.The clinical effects were compared and the patients in each group were compared before and after treatment of the differences in functional indicators and inflammatory factors.Results The total effective rate of the observation group was 97.50%,which was significantly better than that of the control group(χ^2=7.31,P<0.05).After treatment,the blood oxygen partial pressure(92.04±1.15)mmHg and oxygenation index(376.49±10.38)in the observation group were significantly higher than in the control group,and the partial pressure of carbon dioxide(35.02±1.03)mmHg was lower than that of the control group(t=16.27,10.48,11.58,P<0.05).In the observation group,tumor necrosis factor alpha(11.47±1.03)pg/mL,interleukin-8(99.58±1.04)pg/mL,and C-reactive protein(35.99±1.32)mg/L were lower than the control group(t=10.38,20.41,21.48,P<0.05).Conclusion Patients with bronchiectasis and infection have better bronchoscopy and alveolar lavage,which can improve the respiratory function and reduce the level of inflammatory factors.It is worthy of clinical application.
作者
陈刚
CHEN Gang(Department of Respiratory,Nanjing Gaochun People's Hospital,Nanjing,Jiangsu Province,211300 China)
出处
《世界复合医学》
2019年第9期48-50,共3页
World Journal of Complex Medicine
关键词
支气管镜
肺泡灌洗
支气管扩张合并感染
呼吸功能
炎性因子
Bronchoscopy
Alveolar lavage
Bronchiectasis with infection
Respiratory function
Inflammatory factors
