摘要
目的探讨慢性阻塞性肺疾病(COPD)合并肺曲霉菌感染双源薄层CT图像特征及与预后的关系。方法回顾分析2015年1月至2018年5月福建医科大学附属南平第一医院收治的86例疑似合并肺曲霉菌感染的COPD患者临床资料,总结双源薄层CT检查对COPD合并肺曲霉菌感染的诊断情况以及图像表现。结果86例疑似合并肺曲霉菌感染的COPD患64例被证实,其中预后良好48例和预后不良16例。双源薄层CT对COPD合并肺曲霉菌感染诊断的灵敏度和特异度分别为94.20%和78.62%,阳性和阴性预测值分别为92.02%和82.16%。在双源薄层CT检查中,合并肺曲霉菌感染COPD中斑片渗出影最为常见,而空洞征象最为少见,且其病灶大多为双肺多发,上叶和外周带分布较多,而左肺分布较少。预后良好患者其斑片渗出影、晕轮征、双肺纹理粗乱、实变影、胸腔积液、空气新月征、结节影和空洞相关肺部征象出现率显著低于预后不良患者(P<0.05)。结论双源薄层CT检查对COPD合并肺曲霉菌感染诊断率较高,且其相关肺部征象表现与该患者具有一定的相关性,对其预后也具有一定的评估价值。
Objective To investigate the image characteristics of dual-source thin-layer CT of chronic obstructive pulmonary disease(COPD)combined with pulmonary aspergillosis and its relationship with prognosis.Methods The clinical data of 86 COPD patients suspected of pulmonary aspergillosis who were treated in Nanping First Hospital Affiliated to Fujian Medical University from January 2015 to May 2018 were retrospectively analyzed.The diagnosis and the image characteristics of dual-source thin-layer CT examination for COPD combined with pulmonary aspergillosis were summarized.Results In 86 COPD patients suspected with pulmonary aspergillosis,64 cases were confirmed.Among them,48 cases had a good prognosis in and 16 had a poor prognosis.The sensitivity and specificity of dual-source thin-layer CT for the diagnosis of COPD combined with pulmonary aspergillosis were 94.20%and 78.62%,respectively,and the positive and negative predictive values were 92.02%and 82.16%,respectively.In the dual-source thin-layer CT examination,patch exudation shadow was the most common in COPD combined with pulmonary aspergillosis,halo sign were the most rare,and most of the lesions were bilateral pulmonary and multiple,and the upper lobe and peripheral bands were more distributed and left lungs were less distributed.The incidence of patch exudation shadow,halo sign,coarse lung texture,consolidation shadow,pleural effusion,air crescent sign,nodule shadow and lung signs related to cavity of patients with good prognosis was significantly lower than those of patients with poor prognosis(P<0.05).Conclusion Dual-source thin-layer CT examination has a good diagnostic value for COPD combined with pulmonary aspergillosis,and its related lung signs have a certain correlation with the patient,and it has certain evaluation value for its prognosis.
作者
程利
杨家友
陈月华
叶翊翔
CHENG Li;YANG Jia-you;CHEN Yue-hua(Department of Respiratory Medicine,Nanping First Hospital Affiliated to Fujian Medical University,Nanping 353000,Fujian Province,China)
出处
《中国CT和MRI杂志》
2019年第11期45-47,共3页
Chinese Journal of CT and MRI
基金
福建省自然科学基金资助项目(No.2016J01532)
关键词
慢性阻塞性肺疾病
肺曲霉菌感染
双源薄层CT
预后
相关性
Chronic Obstructive Pulmonary Disease
Pulmonary Aspergillosis
Dualsource Thin-layer CT
Prognosis
Correlation
