摘要
目的调查青岛地区妊娠妇女尿碘水平,为妊娠妇女科学补碘提供依据。方法对青岛地区484名妊娠妇女尿碘水平和血清促甲状腺素(TSH)、游离甲状腺素(FT4)水平进行检测。依据世界卫生组织(WHO)推荐的评价标准,评价妊娠妇女碘营养水平。结果484名妊娠妇女中,碘缺乏(尿碘<150μg/L)占19.42%,碘适量(尿碘为150μg/L~<250μg/L)占27.07%,碘过量(尿碘>250μg/L)占53.51%。早、中、晚孕期妊娠妇女碘缺乏比例分别为10.65%、21.14%、28.93%,孕晚期碘缺乏所占比例明显高于孕早期(P<0.05),与孕中期比较差异无统计学意义(P>0.05)。碘适量组血清TSH水平高于碘缺乏组(P<0.05),不同尿碘水平各组之间血清FT4水平差异均无统计学意义(P>0.05)。结论青岛地区妊娠妇女碘营养水平总体良好,部分妊娠妇女碘缺乏。妊娠期碘水平对TSH有一定影响。建议加强妊娠妇女尿碘水平监测和甲状腺功能筛查,并指导妊娠妇女科学补碘。
Objective To investigate the iodine nutritional status of pregnant women in Qingdao,and to provide a reference for iodine intake for pregnant women properly. Methods Urinary levels of iodine and serum levels of free thyroxine(FT4) and thyroid stimulating hormone(TSH) of 484 pregnant women were determined, and the iodine nutritional status of pregnant women was evaluated according to the standards recommended by World Health Organization(WHO). Results Among the 484 pregnant women,pregnant women of urinary iodine <150 μg/L accounted for 19.42%,those of 150-<250 μg/L and >250 μg/L accounted for 27.07% and 53.51%,respectively. The proportions of iodine deficiency of early,middle and late pregnant women were 10.65%,21.14% and 28.93%, respectively. The proportion of iodine deficiency of late pregnant women was higher than that of early pregnant women (P<0.05). There was no statistical significance between middle and late pregnant women(P>0.05). The levels of TSH were higher in pregnant women with urinary iodine 150-<250 μg/L than in pregnant women with urinary iodine <150 μg/L(P<0.05). The levels of FT4 had no statistical significance among different urinary iodine groups (P>0.05). Conclusions The iodine nutritional status for pregnant women in Qingdao is fine,but still some individuals expose in iodine insufficiency. Iodine nutritional status in pregnant women has an effect on TSH levels. It's suggested that urinary iodine monitoring and thyroid function screening should be conducted in pregnant women, which could guide iodine intake for pregnant women properly.
作者
韦涌涛
王松霞
WEI Yongtao;WANG Songxia(Department of Clinical Laboratory,Qingdao Eighth People's Hospital,Qingdao 266100,Shandong,China;Department of Blood Transfusion,Qingdao Eighth People's Hospital,Qingdao 266100,Shandong,China)
出处
《检验医学》
CAS
2019年第10期905-907,共3页
Laboratory Medicine
关键词
碘
尿液
碘缺乏
促甲状腺素
游离甲状腺素
妊娠妇女
Iodine
Urine
Iodine deficiency
Thyroid stimulating hormone
Free thyroxine
Pregnant women
