摘要
目的探究血清降钙素原(PCT)、C反应蛋白(CRP)检测在肝硬化合并肺部感染中的诊断价值。方法分别于我院2017年12月至2018年12月收治的肝硬化合并肺部细菌感染患者、肝硬化患者(未出现其他感染患者)和健康体检人群中各随机抽取40例作为研究对象,并将其分别设为观察组、对照组和空白组。比较三组受检者的血清PCT、CRP及白细胞(WBC)和中性粒细胞百分比(NEU%)水平,并比较观察组与对照组患者的血清PCT、CRP、WBC、NEU%阳性率。结果观察组患者的PCT、CRP、WBC水平及NEU%均明显高于对照组和空白组,差异具有统计学意义(P<0.05);对照组患者的PCT、CRP、WBC水平及NEU%均高于空白组,差异具有统计学意义(P<0.05)。观察组患者的PCT、CRP阳性率均明显高于对照组,差异具有统计学意义(P<0.05);观察组患者的WBC、NEU%阳性率与对照组比较,差异无统计学意义(P>0.05)。结论对肝硬化合并肺部细菌感染患者采用PCT与CRP联合检测,有助于判断患者病情进展,可以作为判断患者治疗、预后等重要参考指标,值得临床推广应用。
Objective To explore the diagnostic value of serum procalcitonin (PCT) and C-reaction protein (CRP) for liver cirrhosis with pulmonary infection. Methods Forty patients with liver cirrhosis complicated with pulmonary bacterial infection, patients with liver cirrhosis (without other infections) and healthy people from December 2017 to December 2018 in our hospital were randomly selected respectively as research subjects and divided into observation group, control group and blank group. The levels of serum PCT, CRP, white blood cell (WBC) and neutrophil percentage (NEU%) among the three groups were compared, and the positive rates of serum PCT, CRP, WBC and NEU% were compared between the observation group and the control group. Results The levels of PCT, CRP, WBC and NEU% in the observation group were significantly higher than those in the control group and the blank group, and the differences were statistically significant (P<0.05);the levels of PCT, CRP, WBC and NEU% in the control group were higher than those in the blank group, and the differences were statistically significant (P<0.05). The positive rates of PCT and CRP in the observation group were significantly higher than those in the control group, and the difference were statistically significant (P<0.05);there were no significant differences in the positive rates of WBC and NEU% between the observation group and the control group (P>0.05). Conclusion The combined detection of PCT and CRP in patients with liver cirrhosis complicated with pulmonary bacterial infection is helpful to judge the progress of patients' disease, and can be used as an important reference index for judging the treatment and prognosis of patients. It is worthy of clinical promotion and application.
作者
祝雪菲
尹朝云
ZHU Xue-fei;YIN Chao-yun(Lantian County People's Hospital,Xi'an 710500;Yan'an Baotashan Hospital,Yan'an 716000,China)
出处
《临床医学研究与实践》
2019年第31期108-110,共3页
Clinical Research and Practice
关键词
肝硬化
肺部细菌感染
PCT
CRP
liver cirrhosis
pulmonary bacterial infection
PCT
CRP
