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MRI-DWI评估肝癌经导管肝动脉化疗栓塞术后临床疗效 被引量:8

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摘要 目的 探讨磁共振弥散加权成像(MRI-DWI)对肝癌经导管肝动脉化疗栓塞术(TACE)术后临床疗效的评价价值。方法 选取2016年1月至2018年7月重庆市涪陵中心医院TACE治疗的肝癌患者230例,分别于术前、术后一个月对患者行MRI-DWI检查,观察并记录表观弥散系数(ADC)值、强化率(CER动脉期)和信号比(SIR动脉期),根据RECIST标准将治疗后患者分为有效组和无效组,分别比较上述参数在两组间差异。结果 共纳入患者230例,共检出肝癌病灶284个,肿瘤平均直径为(7.02±2.21)cm。肝癌患者TACE术后瘤灶ADC值较术前明显增加,CER动脉期和SIR动脉期较术前明显减少(P<0.05)。TACE治疗有效组和无效组术前ADC值、CER动脉期和SIR动脉期差异无统计学意义,术后有效组ADC值大于无效组,CER动脉期和SIR动脉期小于无效组(P均<0.05)。结论 MRI-DWI可有效评估肝细胞肝癌患者TACE术后的病灶大小及坏死程度,对评估治疗效果、术后早期复发等具有重要价值,能够为进一步治疗提供参考依据。
出处 《现代消化及介入诊疗》 2019年第10期1183-1186,共4页 Modern Interventional Diagnosis and Treatment in Gastroenterology
基金 西藏自治区自然科学基金(XZ2017ZR-ZY035)
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