摘要
目的:建立测定十五味消炎止咳口服液中绿原酸及黄芩苷含量的方法。方法:采用高效液相色谱法（HPLC）法,流动相为乙腈-醋酸,流速为0.8ml/min,检测波长为326nm、274nm。结果:绿原酸的回收率为96.8％～104.5％（RSD=1.09％～3 12％）,黄芩苷的回收率为94.9％～97.7％（RSD=1.19％～1.76％）。结论:本测定方法简单可行,重复性好,可作为建立该药质量标准的参考依据。
OBJECTIVE:To establish a method for determination of the contents of chlorogenic acid and baicalin in Shiwuwei Xiaoyanzhike oral liquid .METHODS:HPLC was used,the mobile phase was acetonitrile - acetic acid,the flow rate was 0.8ml/ min and the detecting wavelengths were 326nm and 274nm.RESULTS: The recoveries of chlorogenic acid and baicalin were 96.8% - 104.5% , 94.9% -97.7% and RSD were 1.09% -3.12% , 1.19% -1.76% (n = 3), respectively .CONCLUSION: The method is simple and feasible with a good reproducibility, the RESULTS: can provide a basis for establishing the quality standard of this oral liquid.
出处
《中国药房》
CAS
CSCD
2002年第11期687-688,共2页
China Pharmacy
