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抑郁症神经内分泌功能及其对电针治疗反应的研究 被引量:17

THE RELATIONSHIP BETWEEN THE NEUROBIOCHEMICAL AND NEUROENDOCRINE DYSFUNCTION AND THE RESPONSES TO ELECTRO-ACUPUNCTURE AND AMITRIPTYLINE TREATMENT IN DEPRESSIVE PATIENTS
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摘要 本研究以61例中、重度抑郁症病人为对象,阿米替林为对照,对电针治疗抑郁症的临床和实验室特点及其机理作了初步研究。发现电针与阿米替林一样具有抗抑郁作用,它对双相抑郁症病人或治疗前尿3-甲氧基-4羟基-苯乙二醇硫酸盐(MHPG·SO_4)排泄量低的病人疗效较好,能使伴有内分泌功能异常的病人症状改善。电针治疗后抑郁症病人尿MHPG·SO_4排泄量增加,部分病人内分泌功能恢复正常。研究资料提示,电针的抗抑郁作用与它对中枢NE活动的影响有关。 A blind comparative research was performed in 61 depressive inpatients to study the effects ofelectric acupuncture and amitriptyline and biochemical changes caused by electric acupuncture and ami-triptyline treatment.It was found that the effects of electric acupuncture and amitriptyline were simi-lar and the effect Of electric acupuncture was better in bipolar patients or in patients with lowerpretreatment urinary MHPG.SO_4 excretion.After treatment, urinary MHPG.SO_4 excretion was incre-ased and abnormal DST or TRH-ST was reversed in some patients. The data suggest that the antide-pression mechanism of electric acupuncture 18 related to neurotransmitters.
出处 《北京医科大学学报》 CSCD 1992年第5期401-403,共3页 Journal of Peking University(Health Sciences)
基金 国家教委高校博士学科点专项科研基金
关键词 抑郁症 电针 针灸疗法 Depression Dexamethasone-supperession-test Thyrotropin releasing hormone-stimulation-test MHPG·SO_2 Electro-acupuncture Amitriptyline
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参考文献2

  • 1罗和春,Acupuncture,1990年,1卷,20页
  • 2Zhang Wenhe,Intern J Neuroscience,1981年,14卷,179页

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