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抗肿瘤新药STI571研究新进展 被引量:7

Advances in the new anti-cancers drug STI571
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摘要 STI5 71是近年开发的用于治疗慢性髓细胞性白血病 (CML)的酪氨酸激酶抑制剂 ,对bcr abl激酶有高度特异性的抑制作用。由于该药物是在理解疾病分子机制的基础上 ,针对CML特异的分子异常进行的一种靶向治疗 ,因而与传统化疗药物有很大的不同 ,从而引起了人们的普遍关注。现介绍其作用机制、体内外抗瘤作用、临床试验结果及耐药性等的最新进展。
作者 陈黎明
出处 《国外医学(肿瘤学分册)》 2002年第5期333-337,共5页 Foreign Medical Sciences (Cancer Section)
基金 国家自然科学基金资助项目 ( 3 980 0 182 )。
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